TY - JOUR
T1 - Treatment of Severe Hypervolemic Hyponatremia in a Child with Pneumonia
AU - Genoni, Teresa
AU - Tenconi, Rossana
AU - Bertolozzi, Giuseppe
AU - Laicini, Emanuela Anna
AU - Tardini, Giacomo
AU - Vianello, Federica
AU - Leva, Ernesto
AU - Milani, Gregorio Paolo
AU - Fossali, Emilio Filippo
PY - 2016/6/1
Y1 - 2016/6/1
N2 - A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq/L), low plasma osmolarity (241 mOsm/L), and high urine osmolarity (435 mOsm/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.
AB - A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq/L), low plasma osmolarity (241 mOsm/L), and high urine osmolarity (435 mOsm/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.
KW - diuretics
KW - hyponatremia
KW - intravenous fluids
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U2 - 10.1097/PEC.0000000000000823
DO - 10.1097/PEC.0000000000000823
M3 - Article
AN - SCOPUS:84974593592
VL - 32
SP - 390
EP - 391
JO - Pediatric Emergency Care
JF - Pediatric Emergency Care
SN - 0749-5161
IS - 6
ER -