Treatment of significant carotid artery stenosis in 1824 patients

D. Mazzaccaro, S. Stegher, M. T. Occhiuto, G. Malacrida, M. Caldana, D. G. Tealdi, G. Nano

Research output: Contribution to journalArticlepeer-review


Aim: We report our experience of thirteen years of treatment of significant carotid artery stenosis. Methods: Data of all consecutive patients who came to our Division for a significant carotid artery stenosis from January 1999 to January 2012 were collected about patients' demographic, cardiovascular risk factors, neurological symptoms and treatment (carotid endarterectomy, carotid artery stenting or best medical therapy). Retrospective review was performed and the occurrence of death, major cerebrovascular events (major stroke, minor stroke) and myocardial infarction (MI) were recorded both at 30-day and at long-term. Analysis was performed among groups by means of JMP 5.1®. Results: Of 1824 patients who were admitted to our Department for a significant carotid stenosis, 582 were unsuitable for surgery and underwent carotid artery stenting (CAS, Group A). Three hundred and seventy-three of them were symptomatic (64.1%). Carotid endarterectomy (CEA) was performed in 1030 patients (Group B), 741 (71.9%) of them were symptomatic. The remaining patients (Group C) were treated using best medical therapy (BMT). At 30-day CEA compared to CAS and BMT was associated with higher risk of MI (2.1% vs. 0.2%, and 0.4% respectively, P

Original languageEnglish
Pages (from-to)107-118
Number of pages12
JournalJournal of Cardiovascular Surgery
Issue number1
Publication statusPublished - Feb 1 2015


  • Carotid arteries
  • Complications
  • Retrospective studies
  • Stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Medicine(all)


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