Treatment of single brain metastases

L. Gandola, P. Navarria, F. Lombardi

Research output: Contribution to journalArticlepeer-review


Brain metastases (BrM) occur in 30% to 50% of patients with malignant tumours and represent a relevant cause of morbidity and mortality. As documented by the extensive clinical use of magnetic resonance imaging with contrast enhancement, 25% to 35% of patients with BrM have a single localisation to the brain. Conventional therapeutic options for single BrM consist of either neurosurgery, or whole brain irradiation, or a combination of both. Treatment finality for the majority of the patients is palliation and life expectancy is in the order of a few months. In the last decade, the development of radiosurgery has represented an important advancement in the treatment of patients with BrM. This radiotherapeutic technique represents a possible non-invasive alternative to surgical exeresis for patients with lesions

Original languageEnglish
Pages (from-to)38-44
Number of pages7
JournalFORUM - Trends in Experimental and Clinical Medicine
Issue number1
Publication statusPublished - 2001


  • Neurosurgery
  • Radiosurgery
  • Single brain metastasis
  • Whole brain radiotherapy

ASJC Scopus subject areas

  • Medicine(all)


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