TRATTAMENTO DEI SINTOMI ACUTI DELLA MALATTIA EMORROIDARIA CON O-(β-IDROSSIETIL)-RUTOSIDEA AD ALTE DOSI PER VIA ORALE

Translated title of the contribution: Treatment of the acute symptoms of haemorrhoids with high oral doses of O-(β-hydroxyethyl)-rutosides

F. Annoni, P. Boccasanta, D. Chiurazzi, E. Mozzi, V. Oberhauser

Research output: Contribution to journalArticle

Abstract

Pharmacological treatment is widely used in the therapy of haemorrhoids. An efficient treatment is particularly useful in case of haemorrhoids of the 2nd, 3rd and 4th degree, when phlogosis, oedema and pain are present. Forty patients were treated with either O-(β-hydroxyethyl)-rutosides (4 g/day orally) or placebo in a double blind randomized comparative trial. The treatment groups were homogeneous. O-(β-hydroxyethyl)-rutosides induced a statistically significant reduction of pain and bleeding; placebo did not induce any significant improvement. Tolerability was good and similar for both treatments. It has never been necessary to stop treatment for side effects. The results obtained in this study confirm the usefulness of an oral treatment, and not only local treatment, to patients with acute symptoms of haemorrhoids, both in case of intermittent treatment and in case it is used to prepare the patient for surgery.

Original languageItalian
Pages (from-to)1663-1668
Number of pages6
JournalMinerva Medica
Volume77
Issue number37
Publication statusPublished - 1986

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Annoni, F., Boccasanta, P., Chiurazzi, D., Mozzi, E., & Oberhauser, V. (1986). TRATTAMENTO DEI SINTOMI ACUTI DELLA MALATTIA EMORROIDARIA CON O-(β-IDROSSIETIL)-RUTOSIDEA AD ALTE DOSI PER VIA ORALE. Minerva Medica, 77(37), 1663-1668.