TY - JOUR
T1 - TRATTAMENTO DEI SINTOMI ACUTI DELLA MALATTIA EMORROIDARIA CON O-(β-IDROSSIETIL)-RUTOSIDEA AD ALTE DOSI PER VIA ORALE
AU - Annoni, F.
AU - Boccasanta, P.
AU - Chiurazzi, D.
AU - Mozzi, E.
AU - Oberhauser, V.
PY - 1986
Y1 - 1986
N2 - Pharmacological treatment is widely used in the therapy of haemorrhoids. An efficient treatment is particularly useful in case of haemorrhoids of the 2nd, 3rd and 4th degree, when phlogosis, oedema and pain are present. Forty patients were treated with either O-(β-hydroxyethyl)-rutosides (4 g/day orally) or placebo in a double blind randomized comparative trial. The treatment groups were homogeneous. O-(β-hydroxyethyl)-rutosides induced a statistically significant reduction of pain and bleeding; placebo did not induce any significant improvement. Tolerability was good and similar for both treatments. It has never been necessary to stop treatment for side effects. The results obtained in this study confirm the usefulness of an oral treatment, and not only local treatment, to patients with acute symptoms of haemorrhoids, both in case of intermittent treatment and in case it is used to prepare the patient for surgery.
AB - Pharmacological treatment is widely used in the therapy of haemorrhoids. An efficient treatment is particularly useful in case of haemorrhoids of the 2nd, 3rd and 4th degree, when phlogosis, oedema and pain are present. Forty patients were treated with either O-(β-hydroxyethyl)-rutosides (4 g/day orally) or placebo in a double blind randomized comparative trial. The treatment groups were homogeneous. O-(β-hydroxyethyl)-rutosides induced a statistically significant reduction of pain and bleeding; placebo did not induce any significant improvement. Tolerability was good and similar for both treatments. It has never been necessary to stop treatment for side effects. The results obtained in this study confirm the usefulness of an oral treatment, and not only local treatment, to patients with acute symptoms of haemorrhoids, both in case of intermittent treatment and in case it is used to prepare the patient for surgery.
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M3 - Articolo
C2 - 3531924
AN - SCOPUS:0022506117
VL - 77
SP - 1663
EP - 1668
JO - Minerva Medicolegale e Archivio di Antropologia Criminale
JF - Minerva Medicolegale e Archivio di Antropologia Criminale
SN - 0026-4806
IS - 37
ER -