Treatment of the chronic total occlusion

A call to action for the interventional community

Mauro Carlino, Caroline J. Magri, Barry F. Uretsky, Emmanouil S. Brilakis, Simon Walsh, James C. Spratt, Colm Hanratty, J. Aaron Grantham, Stéphane Rinfret, Craig A. Thompson, William L. Lombardi, Alfredo R. Galassi, George Sianos, Azeem Latib, Roberto Garbo, Dimitri Karmpaliotis, David E. Kandzari, Antonio Colombo

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

There is substantial evidence that recanalization of a chronic total occlusion is beneficial; nonetheless, it is generally underutilized in clinical practice. We consider the Aesop's fable of the "Fox and the Grapes" as analogous to the current situation in interventional cardiology. The technical challenges in achieving CTO recanalization has led interventionalists, clinical cardiologists, and sometimes even patients to believe that CTO recanalization is not effective, and, therefore, not needed. This perspective reviews available data regarding efficacy and safety of CTO percutaneous coronary intervention (PCI) in the current drug-eluting stent era, discusses areas where more studies are required, and encourages the interventional community to utilize CTO PCI where appropriate based on current evidence.

Original languageEnglish
Pages (from-to)771-778
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Volume85
Issue number5
DOIs
Publication statusPublished - Apr 1 2015

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Percutaneous Coronary Intervention
Drug-Eluting Stents
Vitis
Cardiology
Safety
Therapeutics
Cardiologists

Keywords

  • chronic total occlusions
  • coronary artery bypass grafting
  • coronary artery disease
  • myocardial infarction
  • percutaneous coronary intervention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Treatment of the chronic total occlusion : A call to action for the interventional community. / Carlino, Mauro; Magri, Caroline J.; Uretsky, Barry F.; Brilakis, Emmanouil S.; Walsh, Simon; Spratt, James C.; Hanratty, Colm; Grantham, J. Aaron; Rinfret, Stéphane; Thompson, Craig A.; Lombardi, William L.; Galassi, Alfredo R.; Sianos, George; Latib, Azeem; Garbo, Roberto; Karmpaliotis, Dimitri; Kandzari, David E.; Colombo, Antonio.

In: Catheterization and Cardiovascular Interventions, Vol. 85, No. 5, 01.04.2015, p. 771-778.

Research output: Contribution to journalArticle

Carlino, M, Magri, CJ, Uretsky, BF, Brilakis, ES, Walsh, S, Spratt, JC, Hanratty, C, Grantham, JA, Rinfret, S, Thompson, CA, Lombardi, WL, Galassi, AR, Sianos, G, Latib, A, Garbo, R, Karmpaliotis, D, Kandzari, DE & Colombo, A 2015, 'Treatment of the chronic total occlusion: A call to action for the interventional community', Catheterization and Cardiovascular Interventions, vol. 85, no. 5, pp. 771-778. https://doi.org/10.1002/ccd.25736
Carlino, Mauro ; Magri, Caroline J. ; Uretsky, Barry F. ; Brilakis, Emmanouil S. ; Walsh, Simon ; Spratt, James C. ; Hanratty, Colm ; Grantham, J. Aaron ; Rinfret, Stéphane ; Thompson, Craig A. ; Lombardi, William L. ; Galassi, Alfredo R. ; Sianos, George ; Latib, Azeem ; Garbo, Roberto ; Karmpaliotis, Dimitri ; Kandzari, David E. ; Colombo, Antonio. / Treatment of the chronic total occlusion : A call to action for the interventional community. In: Catheterization and Cardiovascular Interventions. 2015 ; Vol. 85, No. 5. pp. 771-778.
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