TY - JOUR
T1 - Treatment of the pregnant mother with cancer
T2 - A systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part II: Hematological tumors
AU - Azim, Hatem A.
AU - Pavlidis, Nicholas
AU - Peccatori, Fedro A.
PY - 2010/4
Y1 - 2010/4
N2 - Managing pregnant patients with hematological tumors pose even more conflicts compared to solid tumors. Unlike the majority of solid tumors, hematological malignancies are potentially curable; hence it is important to deliver the best treatment options available, which sometimes could be too aggressive to deliver during pregnancy.In part II, we report the results of women with hematological malignancies treated with systemic therapies during the course of pregnancy. Lymphoma, acute leukemia and chronic myeloid leukemia were the most commonly treated.We discuss the safety of the different regimens reported and propose alternatives to standardized approaches in case they pose significant risk to the pregnancy and/or the fetus.
AB - Managing pregnant patients with hematological tumors pose even more conflicts compared to solid tumors. Unlike the majority of solid tumors, hematological malignancies are potentially curable; hence it is important to deliver the best treatment options available, which sometimes could be too aggressive to deliver during pregnancy.In part II, we report the results of women with hematological malignancies treated with systemic therapies during the course of pregnancy. Lymphoma, acute leukemia and chronic myeloid leukemia were the most commonly treated.We discuss the safety of the different regimens reported and propose alternatives to standardized approaches in case they pose significant risk to the pregnancy and/or the fetus.
KW - Chemotherapy
KW - Leukemia in pregnancy
KW - Lymphoma in pregnancy
KW - Rituximab
KW - Safety
UR - http://www.scopus.com/inward/record.url?scp=77950614637&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950614637&partnerID=8YFLogxK
U2 - 10.1016/j.ctrv.2009.11.004
DO - 10.1016/j.ctrv.2009.11.004
M3 - Article
C2 - 20018452
AN - SCOPUS:77950614637
VL - 36
SP - 110
EP - 121
JO - Cancer Treatment Reviews
JF - Cancer Treatment Reviews
SN - 0305-7372
IS - 2
ER -