Treatment of the pregnant mother with cancer: A systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part II: Hematological tumors

Hatem A. Azim, Nicholas Pavlidis, Fedro A. Peccatori

Research output: Contribution to journalArticle

Abstract

Managing pregnant patients with hematological tumors pose even more conflicts compared to solid tumors. Unlike the majority of solid tumors, hematological malignancies are potentially curable; hence it is important to deliver the best treatment options available, which sometimes could be too aggressive to deliver during pregnancy.In part II, we report the results of women with hematological malignancies treated with systemic therapies during the course of pregnancy. Lymphoma, acute leukemia and chronic myeloid leukemia were the most commonly treated.We discuss the safety of the different regimens reported and propose alternatives to standardized approaches in case they pose significant risk to the pregnancy and/or the fetus.

Original languageEnglish
Pages (from-to)110-121
Number of pages12
JournalCancer Treatment Reviews
Volume36
Issue number2
DOIs
Publication statusPublished - Apr 2010

Keywords

  • Chemotherapy
  • Leukemia in pregnancy
  • Lymphoma in pregnancy
  • Rituximab
  • Safety

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Treatment of the pregnant mother with cancer: A systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part II: Hematological tumors'. Together they form a unique fingerprint.

  • Cite this