Trattamento con immunoglobuline nella porpora trombotica trombocitopenica

Thrombotic thrombocytopenic purpura (TTP) is an uncommon syndrome and its course, in most cases acute, may in some circumstances assume a recidivious character. The rarity of this form of the disease and the gravity of its prognosis justify the difficulty to define a definitive care protocol. We report a case of TTP treated with steroids, fresh frozen plasma and finally with high-dose IgG (HDIgG). Data of hematological parameters during the different phases of treatment with HDIgG are shown in this report. The favourable outcome of our case suggests the use of HDIgG as a valid alternative in the treatment of TTP.