Treatment of venous thromboembolism in patients with cancer: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET)Tiziano Barbui, Professor, Fondazione Ospedale Maggiore, Bergamo, ItalyDavide Tassinari, Supportive and Palliative Care Unit, Department of Oncology, City Hospital, Rimini, Italy.

Davide Imberti, Marcello Di Nisio, Maria Benedetta Donati, Anna Falanga, Angelo Ghirarduzzi, Daniele Guarneri, Franco Piovella, Rita Carlotta Santoro, Edoardo Baldini, Stefania Zampogna

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The treatment of venous thromboembolism (VTE) in cancer patients remains controversial. Purpose: The Italian Society for Thrombosis and Haemostasis (SISET) commissioned a project to develop clinical practice guidelines for the therapy of VTE in patients with malignancies. Methods: Key questions about the treatment of VTE in patients with malignancies were formulated by a multidisciplinary working group consisting of experts in clinical medicine and research. After a systematic review and discussion of the literature, recommendations were formulated and graded according to the supporting evidence. For those questions for which the literature search did not yield any definitive answer (absence of evidence evidence of low quality, and contradictory evidence), a formal consensus method was used to issue clinical recommendations. Results: The results of the available literature on VTE treatment in cancer patients were reviewed and clinical recommendations were drafted. Conclusion: We describe the results of a systematic literature review and an explicit approach to consensus techniques which resulted in recommendations for the key therapeutic issues in cancer patients with VTE.

Original languageEnglish
JournalThrombosis Research
Volume124
Issue number5
DOIs
Publication statusPublished - Nov 2009

ASJC Scopus subject areas

  • Hematology

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