Abstract
We used liposomal amphotericin B as first-choice treatment of visceral leishmaniasis in 106 immunocompetent children who acquired the infection in a temperate region of southern Europe (Italy) where Leishmania infantum visceral leishmaniasis is endemic. The aim of the study was to identify the minimum total dose of liposomal amphotericin B needed to cure the infection in children and reduce the period of hospitalization. We conclude that the optimal regimen in immunocompetent children with L. infantum visceral leishmaniasis to be a total dose of 18 mg/kg of liposomal amphotericin B (3 mg/kg per day for 5 days, followed by 3 mg/kg administered as an outpatient regimen on day 10).
Original language | English |
---|---|
Pages (from-to) | 271-277 |
Number of pages | 7 |
Journal | Journal of Pediatrics |
Volume | 131 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1997 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health