Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Maria Elena Laino; Serena Monti; David S Klimstra; Laura H Tang; Lorenzo Mannelli

doi:10.1097/MPH.0000000000001362

Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Maria Elena Laino, Serena Monti, David S Klimstra, Laura H Tang, Lorenzo Mannelli

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Abstract

A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

Original language	English
Journal	Journal of Pediatric Hematology/Oncology
DOIs	https://doi.org/10.1097/MPH.0000000000001362
Publication status	E-pub ahead of print - Nov 28 2018

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title = "Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases",

abstract = "A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.",

author = "Laino, {Maria Elena} and Serena Monti and Klimstra, {David S} and Tang, {Laura H} and Lorenzo Mannelli",

year = "2018",

month = nov,

day = "28",

doi = "10.1097/MPH.0000000000001362",

language = "English",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

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T1 - Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

AU - Laino, Maria Elena

AU - Monti, Serena

AU - Klimstra, David S

AU - Tang, Laura H

AU - Mannelli, Lorenzo

PY - 2018/11/28

Y1 - 2018/11/28

N2 - A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

AB - A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

U2 - 10.1097/MPH.0000000000001362

DO - 10.1097/MPH.0000000000001362

M3 - Article

C2 - 30499907

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

ER -

Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Abstract

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