Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Maria Elena Laino; Serena Monti; David S Klimstra; Laura H Tang; Lorenzo Mannelli

doi:10.1097/MPH.0000000000001362

Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Maria Elena Laino, Serena Monti, David S Klimstra, Laura H Tang, Lorenzo Mannelli

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Abstract

A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

Original language	English
Journal	Journal of Pediatric Hematology/Oncology
DOIs	https://doi.org/10.1097/MPH.0000000000001362
Publication status	E-pub ahead of print - Nov 28 2018

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Laino, M. E., Monti, S., Klimstra, D. S., Tang, L. H., & Mannelli, L. (2018). Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases. Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/MPH.0000000000001362

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abstract = "A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.",

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AU - Mannelli, Lorenzo

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