Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

Maria Elena Laino, Serena Monti, David S Klimstra, Laura H Tang, Lorenzo Mannelli

Research output: Contribution to journalArticlepeer-review


A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

Original languageEnglish
JournalJournal of Pediatric Hematology/Oncology
Publication statusE-pub ahead of print - Nov 28 2018


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