Trattamento con Topiramato come terapia aggiuntiva in pazienti adulti con ritardo mentale

Translated title of the contribution: Treatment with Topiramate as add on therapy in adult patients with mental retardation

F. Dalpozzo, L. Discepolo, G. De Polo, A. Martinuzzi

Research output: Contribution to journalArticle

Abstract

To describe our experience in the use of Topiramate as add-on therapy resistant epileptic patients with mental retardation, we have used TPM in 11 patients with symptomatic epilepsy (partial simplex, partial complex or generalized crisis). The TPM was added 50 mg. weekly to reach the minimum efficacy or 400 mg./die as maximum. A bout 63% of patients dropped out before 6 months because of side effects involving cognitive functions. This would suggest a much slower dose increase in patients with mental retardation.

Original languageItalian
Pages (from-to)175-176
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number113-114
Publication statusPublished - 2001

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Intellectual Disability
Partial Epilepsy
Therapeutics
Cognition
topiramate

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Trattamento con Topiramato come terapia aggiuntiva in pazienti adulti con ritardo mentale. / Dalpozzo, F.; Discepolo, L.; De Polo, G.; Martinuzzi, A.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 113-114, 2001, p. 175-176.

Research output: Contribution to journalArticle

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