Trends in heart failure hospitalizations, patient characteristics, in-hospital and 1-year mortality

A population study, from 2000 to 2012 in Lombardy

Maria Frigerio, Cristina Mazzali, Anna Maria Paganoni, Francesca Ieva, Pietro Vittorio Barbieri, Mauro Maistrello, Ornella Agostoni, Cristina Masella, Simonetta Scalvini, HF Data Project

Research output: Contribution to journalArticle

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Abstract

BACKGROUND: This study was undertaken to evaluate trends in heat failure hospitalizations (HFHs) and 1-year mortality of HFH in Lombardy, the largest Italian region, from 2000 to 2012.

METHODS: Hospital discharge forms with HF-related ICD-9 CM codes collected from 2000 to 2012 by the regional healthcare service (n=699797 in 370538 adult patients), were analyzed with respect to in-hospital and 1-year mortality; Group (G) 1 included most acute HF episodes with primary cardiac diagnosis (70%); G2 included cardiomyopathies without acute HF codes (17%); and G3 included non-cardiac conditions with HF as secondary diagnosis (13%). Patients experiencing their first HFH since 2005 were analyzed as incident cases (n=216782).

RESULTS: Annual HFHs number (mean 53830) and in-hospital mortality (9.4%) did not change over the years, the latter being associated with increasing age (p<0.0001) and diagnosis Group (G1 9.1%, G2 5.6%, G3 15.9%, p<0.0001). Incidence of new cases decreased over the years (3.62 [CI 3.58-3.67] in 2005 to 3.13 [CI 3.09-3.17] in 2012, per 1000 adult inhabitants/year, p<0.0001), with an increasing proportion of patients aged ≥85y (22.3% to 31.4%, p<0.0001). Mortality lowered over time in <75y incident cases, both in-hospital (5.15% to 4.36%, p<0.0001) and at 1-year (14.8% to 12.9%, p=0.0006).

CONCLUSIONS: The overall burden and mortality of HFH appear stable for more than a decade. However, from 2005 to 2012, there was a reduction of new, incident cases, with increasing age at first hospitalization. Meanwhile, both in-hospital and 1-year mortality decreased in patients aged <75y, possibly due to improved prevention and treatment.

Original languageEnglish
Pages (from-to)310-314
Number of pages5
JournalInternational Journal of Cardiology
Volume236
DOIs
Publication statusPublished - Jun 1 2017

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Hospitalization
Heart Failure
Hot Temperature
Mortality
Population
International Classification of Diseases
Hospital Mortality
Cardiomyopathies
Delivery of Health Care
Incidence
Therapeutics

Keywords

  • Journal Article

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Trends in heart failure hospitalizations, patient characteristics, in-hospital and 1-year mortality : A population study, from 2000 to 2012 in Lombardy. / Frigerio, Maria; Mazzali, Cristina; Paganoni, Anna Maria; Ieva, Francesca; Barbieri, Pietro Vittorio; Maistrello, Mauro; Agostoni, Ornella; Masella, Cristina; Scalvini, Simonetta; HF Data Project.

In: International Journal of Cardiology, Vol. 236, 01.06.2017, p. 310-314.

Research output: Contribution to journalArticle

Frigerio, Maria ; Mazzali, Cristina ; Paganoni, Anna Maria ; Ieva, Francesca ; Barbieri, Pietro Vittorio ; Maistrello, Mauro ; Agostoni, Ornella ; Masella, Cristina ; Scalvini, Simonetta ; HF Data Project. / Trends in heart failure hospitalizations, patient characteristics, in-hospital and 1-year mortality : A population study, from 2000 to 2012 in Lombardy. In: International Journal of Cardiology. 2017 ; Vol. 236. pp. 310-314.
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title = "Trends in heart failure hospitalizations, patient characteristics, in-hospital and 1-year mortality: A population study, from 2000 to 2012 in Lombardy",
abstract = "BACKGROUND: This study was undertaken to evaluate trends in heat failure hospitalizations (HFHs) and 1-year mortality of HFH in Lombardy, the largest Italian region, from 2000 to 2012.METHODS: Hospital discharge forms with HF-related ICD-9 CM codes collected from 2000 to 2012 by the regional healthcare service (n=699797 in 370538 adult patients), were analyzed with respect to in-hospital and 1-year mortality; Group (G) 1 included most acute HF episodes with primary cardiac diagnosis (70{\%}); G2 included cardiomyopathies without acute HF codes (17{\%}); and G3 included non-cardiac conditions with HF as secondary diagnosis (13{\%}). Patients experiencing their first HFH since 2005 were analyzed as incident cases (n=216782).RESULTS: Annual HFHs number (mean 53830) and in-hospital mortality (9.4{\%}) did not change over the years, the latter being associated with increasing age (p<0.0001) and diagnosis Group (G1 9.1{\%}, G2 5.6{\%}, G3 15.9{\%}, p<0.0001). Incidence of new cases decreased over the years (3.62 [CI 3.58-3.67] in 2005 to 3.13 [CI 3.09-3.17] in 2012, per 1000 adult inhabitants/year, p<0.0001), with an increasing proportion of patients aged ≥85y (22.3{\%} to 31.4{\%}, p<0.0001). Mortality lowered over time in <75y incident cases, both in-hospital (5.15{\%} to 4.36{\%}, p<0.0001) and at 1-year (14.8{\%} to 12.9{\%}, p=0.0006).CONCLUSIONS: The overall burden and mortality of HFH appear stable for more than a decade. However, from 2005 to 2012, there was a reduction of new, incident cases, with increasing age at first hospitalization. Meanwhile, both in-hospital and 1-year mortality decreased in patients aged <75y, possibly due to improved prevention and treatment.",
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T1 - Trends in heart failure hospitalizations, patient characteristics, in-hospital and 1-year mortality

T2 - A population study, from 2000 to 2012 in Lombardy

AU - Frigerio, Maria

AU - Mazzali, Cristina

AU - Paganoni, Anna Maria

AU - Ieva, Francesca

AU - Barbieri, Pietro Vittorio

AU - Maistrello, Mauro

AU - Agostoni, Ornella

AU - Masella, Cristina

AU - Scalvini, Simonetta

AU - HF Data Project

N1 - Copyright © 2017 Elsevier B.V. All rights reserved.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - BACKGROUND: This study was undertaken to evaluate trends in heat failure hospitalizations (HFHs) and 1-year mortality of HFH in Lombardy, the largest Italian region, from 2000 to 2012.METHODS: Hospital discharge forms with HF-related ICD-9 CM codes collected from 2000 to 2012 by the regional healthcare service (n=699797 in 370538 adult patients), were analyzed with respect to in-hospital and 1-year mortality; Group (G) 1 included most acute HF episodes with primary cardiac diagnosis (70%); G2 included cardiomyopathies without acute HF codes (17%); and G3 included non-cardiac conditions with HF as secondary diagnosis (13%). Patients experiencing their first HFH since 2005 were analyzed as incident cases (n=216782).RESULTS: Annual HFHs number (mean 53830) and in-hospital mortality (9.4%) did not change over the years, the latter being associated with increasing age (p<0.0001) and diagnosis Group (G1 9.1%, G2 5.6%, G3 15.9%, p<0.0001). Incidence of new cases decreased over the years (3.62 [CI 3.58-3.67] in 2005 to 3.13 [CI 3.09-3.17] in 2012, per 1000 adult inhabitants/year, p<0.0001), with an increasing proportion of patients aged ≥85y (22.3% to 31.4%, p<0.0001). Mortality lowered over time in <75y incident cases, both in-hospital (5.15% to 4.36%, p<0.0001) and at 1-year (14.8% to 12.9%, p=0.0006).CONCLUSIONS: The overall burden and mortality of HFH appear stable for more than a decade. However, from 2005 to 2012, there was a reduction of new, incident cases, with increasing age at first hospitalization. Meanwhile, both in-hospital and 1-year mortality decreased in patients aged <75y, possibly due to improved prevention and treatment.

AB - BACKGROUND: This study was undertaken to evaluate trends in heat failure hospitalizations (HFHs) and 1-year mortality of HFH in Lombardy, the largest Italian region, from 2000 to 2012.METHODS: Hospital discharge forms with HF-related ICD-9 CM codes collected from 2000 to 2012 by the regional healthcare service (n=699797 in 370538 adult patients), were analyzed with respect to in-hospital and 1-year mortality; Group (G) 1 included most acute HF episodes with primary cardiac diagnosis (70%); G2 included cardiomyopathies without acute HF codes (17%); and G3 included non-cardiac conditions with HF as secondary diagnosis (13%). Patients experiencing their first HFH since 2005 were analyzed as incident cases (n=216782).RESULTS: Annual HFHs number (mean 53830) and in-hospital mortality (9.4%) did not change over the years, the latter being associated with increasing age (p<0.0001) and diagnosis Group (G1 9.1%, G2 5.6%, G3 15.9%, p<0.0001). Incidence of new cases decreased over the years (3.62 [CI 3.58-3.67] in 2005 to 3.13 [CI 3.09-3.17] in 2012, per 1000 adult inhabitants/year, p<0.0001), with an increasing proportion of patients aged ≥85y (22.3% to 31.4%, p<0.0001). Mortality lowered over time in <75y incident cases, both in-hospital (5.15% to 4.36%, p<0.0001) and at 1-year (14.8% to 12.9%, p=0.0006).CONCLUSIONS: The overall burden and mortality of HFH appear stable for more than a decade. However, from 2005 to 2012, there was a reduction of new, incident cases, with increasing age at first hospitalization. Meanwhile, both in-hospital and 1-year mortality decreased in patients aged <75y, possibly due to improved prevention and treatment.

KW - Journal Article

U2 - 10.1016/j.ijcard.2017.02.052

DO - 10.1016/j.ijcard.2017.02.052

M3 - Article

VL - 236

SP - 310

EP - 314

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -