Trends in net survival from rectal cancer in six European Latin countries: Results from the SUDCAN population-based study

C. Lepage, N. Bossard, O. Dejardin, M.C. Carmona-Garcia, S. Manfredi, J. Faivre, GRELL EUROCARE-5 Working Group, Roberta De Angelis, Sandra Mallone, Paolo Roazzi, Massimiliano Caldora, E. Carrani, Silvia Giovanna Luisa Francisci, Daniela Pierannunzio, Silvia Rossi, Mariano Santaquilani, andrea tavilla

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare the net survival from rectal cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000-2004 using the Pohar-Perme estimator. For trend analyses, the study-period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain, and Switzerland and from 2000 to 2004 in Belgium and Portugal. These analyses were carried out using a flexible excess rate modeling strategy. There were some differences between countries in age-standardized net survivals (2000-2004). The 5-year survival ranged from 55% (Portugal) to 62% (Belgium). There was an increase in agestandardized survival rates between 1992 and 2004 as observed at 1 and 5 years. This increase was observed in the 60 and 70-year age groups, but was less marked in the 80-year age group. This was related to a decrease in the excess mortality rates between 1992 and 2004, until ∼24 months after diagnosis in France and Switzerland, whereas it was continuous over the entire study period in Italy and Spain. Considerable improvements in survival from rectal cancer have been achieved. Further improvements are expected through better adherence to the guidelines and the implementation of mass screening. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Original languageEnglish
Pages (from-to)S48-S55
JournalEuropean Journal of Cancer Prevention
Volume26
Issue numbersuppl 1
DOIs
Publication statusPublished - 2017

Fingerprint

Rectal Neoplasms
Survival
Portugal
Belgium
Switzerland
Spain
Italy
Population
France
Mortality
Age Groups
Guideline Adherence
Mass Screening
Survival Rate
Demography
Databases
Health

Keywords

  • Cancer registries
  • Europe
  • Excess mortality rates
  • Net survival
  • Rectal cancer
  • Trends analysis
  • adolescent
  • adult
  • aged
  • Article
  • Belgium
  • cancer survival
  • female
  • follow up
  • France
  • groups by age
  • human
  • Italy
  • major clinical study
  • male
  • multicenter study
  • population research
  • Portugal
  • practice guideline
  • priority journal
  • rectum cancer
  • Spain
  • survival rate
  • Switzerland
  • very elderly
  • epidemiology
  • factual database
  • health survey
  • middle aged
  • mortality
  • procedures
  • rectum tumor
  • register
  • trends
  • young adult
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Databases, Factual
  • Female
  • Humans
  • Male
  • Middle Aged
  • Population Surveillance
  • Rectal Neoplasms
  • Registries
  • Survival Rate
  • Young Adult

Cite this

Trends in net survival from rectal cancer in six European Latin countries: Results from the SUDCAN population-based study. / Lepage, C.; Bossard, N.; Dejardin, O.; Carmona-Garcia, M.C.; Manfredi, S.; Faivre, J.; Group, GRELL EUROCARE-5 Working; De Angelis, Roberta; Mallone, Sandra; Roazzi, Paolo; Caldora, Massimiliano; Carrani, E.; Francisci, Silvia Giovanna Luisa; Pierannunzio, Daniela; Rossi, Silvia; Santaquilani, Mariano; tavilla, andrea.

In: European Journal of Cancer Prevention, Vol. 26, No. suppl 1, 2017, p. S48-S55.

Research output: Contribution to journalArticle

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title = "Trends in net survival from rectal cancer in six European Latin countries: Results from the SUDCAN population-based study",
abstract = "Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare the net survival from rectal cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000-2004 using the Pohar-Perme estimator. For trend analyses, the study-period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain, and Switzerland and from 2000 to 2004 in Belgium and Portugal. These analyses were carried out using a flexible excess rate modeling strategy. There were some differences between countries in age-standardized net survivals (2000-2004). The 5-year survival ranged from 55{\%} (Portugal) to 62{\%} (Belgium). There was an increase in agestandardized survival rates between 1992 and 2004 as observed at 1 and 5 years. This increase was observed in the 60 and 70-year age groups, but was less marked in the 80-year age group. This was related to a decrease in the excess mortality rates between 1992 and 2004, until ∼24 months after diagnosis in France and Switzerland, whereas it was continuous over the entire study period in Italy and Spain. Considerable improvements in survival from rectal cancer have been achieved. Further improvements are expected through better adherence to the guidelines and the implementation of mass screening. Copyright {\circledC} 2017 Wolters Kluwer Health, Inc. All rights reserved.",
keywords = "Cancer registries, Europe, Excess mortality rates, Net survival, Rectal cancer, Trends analysis, adolescent, adult, aged, Article, Belgium, cancer survival, female, follow up, France, groups by age, human, Italy, major clinical study, male, multicenter study, population research, Portugal, practice guideline, priority journal, rectum cancer, Spain, survival rate, Switzerland, very elderly, epidemiology, factual database, health survey, middle aged, mortality, procedures, rectum tumor, register, trends, young adult, Adolescent, Adult, Aged, Aged, 80 and over, Databases, Factual, Female, Humans, Male, Middle Aged, Population Surveillance, Rectal Neoplasms, Registries, Survival Rate, Young Adult",
author = "C. Lepage and N. Bossard and O. Dejardin and M.C. Carmona-Garcia and S. Manfredi and J. Faivre and Group, {GRELL EUROCARE-5 Working} and {De Angelis}, Roberta and Sandra Mallone and Paolo Roazzi and Massimiliano Caldora and E. Carrani and Francisci, {Silvia Giovanna Luisa} and Daniela Pierannunzio and Silvia Rossi and Mariano Santaquilani and andrea tavilla",
note = "Cited By :1 Export Date: 12 April 2018 CODEN: EJUPE Correspondence Address: Lepage, C.; Digestive Cancer Registry of Burgundy, INSERM U866, CHU Dijon, University of BurgundyFrance; email: come.lepage@u-bourgogne.fr Funding details: 20102202 Funding details: Compagnia di San Paolo Funding details: EC, European Commission Funding details: Ligue Contre le Cancer Funding details: Fondazione Cariplo Funding details: RF-2009-1529710 Funding details: HCL, Hospices Civils de Lyon Funding text: The SUDCAN study was supported by the French Ligue contre le Cancer. The authors thank Ludivine Garrier (registre des cancers digestifs de Bourgogne) for her technical assistance and Jean Iwaz (Service de Biostatistique des Hospices Civils de Lyon) for the final revision of the manuscript. The EUROCARE study was supported by The Compagnia di San Paolo, Fondazione Cariplo, the Italian Ministry of Health (Ricerca Finalizzata 2009, RF-2009-1529710) and the European Commission (European Action Against Cancer, EPAAC, Joint Action No. 20102202). References: Allemani, C., Weir, H.K., Carreira, H., Harewood, R., Spika, D., Wang, X.S., Global surveillance of cancer survival 1995-2009: Analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2) (2015) Lancet, 385, pp. 977-1010; Cottet, V., Bouvier, V., Rollot, F., Jooste, V., Bedenne, L., Faivre, J., Incidence and patterns of late recurrences in rectal cancer patients (2015) Ann Surg Oncol, 22, pp. 520-527; Crocetti, E., Bossard, N., Uhry, Z., Roche, L., Rossi, S., Capocaccia, R., Trends in net survival from 15 cancers in six European Latin countries: The SUDCAN population-based study material (2016) Eur J Cancer Prev, 25, pp. S3-S8; Dahlberg, M., Glimelius, B., P{\aa}hlman, L., Improved survival and reduction in local failure rates after preoperative radiotherapy: Evidence for the generalizability of the results of Swedish Rectal Cancer Trial (1999) Ann Surg, 229, pp. 493-497; De Angelis, R., Francisci, S., Baili, P., Marchesi, F., Roazzi, P., Belot, A., The EUROCARE-4 database on cancer survival in Europe: Data standardisation, quality control and methods of statistical analysis (2009) Eur J Cancer, 45, pp. 909-930; De Angelis, R., Sant, M., Coleman, M.P., Francisci, S., Baili, P., Pierannunzio, D., Cancer survival in Europe 1999-2007 by country and age: Results of EUROCARE-5 - A population-based study (2014) Lancet Oncol, 15, pp. 23-34; De Gramont, A., Bosset, J.F., Milan, C., Rougier, P., Bouch{\'e}, O., Etienne, P.L., Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study (1997) J Clin Oncol, 15, pp. 808-815; Desgrippes, R., Bouvier, V., Delafosse, P., Robaszkiewicz, M., Molini{\'e}, F., Tr{\'e}tarre, B., Management of rectal cancer in France in a well-defined population (2014) Eur J Gastroenterol Hepatol, 26, pp. 743-747; Ferlay, J., Soerjomataram, I., Ervik, M., Dikshit, R., Eser, S., Mathers, C., (2013) GLOBOCAN 2012 v10, Cancer Incidence and Mortality Worldwide: IARC Cancerbase No 11, , http://globocan.iarc.fr, Lyon, France: International Agency for Research on Cancer. [Accessed 9 September 2016]; Kapiteijn, E., Marijnen, C.A., Nagtegaal, I.D., Putter, H., Steup, W.H., Wiggers, T., Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer (2001) N Engl J Med, 345, pp. 638-646; Minicozzi, P., Bouvier, A.M., Faivre, J., Sant, M., Management of rectal cancers in relation to treatment guidelines: A population-based study comparing Italian and French patients (2014) Dig Liver Dis, 46, pp. 645-651; Mitry, E., Bouvier, A.M., Esteve, J., Faivre, J., Benefit of operative mortality reduction on colorectal cancer survival (2002) Br J Surg, 89, pp. 1557-1562; Morris, E.J., Taylor, E.F., Thomas, J.D., Quirke, P., Finan, P.J., Coleman, M.P., Thirty-day postoperative mortality after colorectal cancer surgery in England (2011) Gut, 60, pp. 806-813; Perme, M.P., Stare, J., Est{\`e}ve, J., On estimation in relative survival (2012) Biometrics, 68, pp. 113-120; Quipourt, V., Jooste, V., Cottet, V., Faivre, J., Bouvier, A.M., Comorbidities alone do not explain the undertreatment of colorectal cancer in older adults: A French population-based study (2011) J Am Geriatr Soc, 59, pp. 694-698; Smedh, K., Olsson, L., Johansson, H., Aberg, C., Andersson, M., Reduction of postoperative morbidity and mortality in patients with rectal cancer following the introduction of a colorectal unit (2001) Br J Surg, 88, pp. 273-277; Uhry, Z., Bossard, N., Remontet, L., Iwaz, J., Roche, L., New insights into survival trend analyses in cancer population-based studies: The SUDCAN methodology (2016) Eur J Cancer Prev, 25, pp. S9-S15",
year = "2017",
doi = "10.1097/CEJ.0000000000000305",
language = "English",
volume = "26",
pages = "S48--S55",
journal = "European Journal of Cancer Prevention",
issn = "0959-8278",
publisher = "Lippincott Williams and Wilkins",
number = "suppl 1",

}

TY - JOUR

T1 - Trends in net survival from rectal cancer in six European Latin countries: Results from the SUDCAN population-based study

AU - Lepage, C.

AU - Bossard, N.

AU - Dejardin, O.

AU - Carmona-Garcia, M.C.

AU - Manfredi, S.

AU - Faivre, J.

AU - Group, GRELL EUROCARE-5 Working

AU - De Angelis, Roberta

AU - Mallone, Sandra

AU - Roazzi, Paolo

AU - Caldora, Massimiliano

AU - Carrani, E.

AU - Francisci, Silvia Giovanna Luisa

AU - Pierannunzio, Daniela

AU - Rossi, Silvia

AU - Santaquilani, Mariano

AU - tavilla, andrea

N1 - Cited By :1 Export Date: 12 April 2018 CODEN: EJUPE Correspondence Address: Lepage, C.; Digestive Cancer Registry of Burgundy, INSERM U866, CHU Dijon, University of BurgundyFrance; email: come.lepage@u-bourgogne.fr Funding details: 20102202 Funding details: Compagnia di San Paolo Funding details: EC, European Commission Funding details: Ligue Contre le Cancer Funding details: Fondazione Cariplo Funding details: RF-2009-1529710 Funding details: HCL, Hospices Civils de Lyon Funding text: The SUDCAN study was supported by the French Ligue contre le Cancer. The authors thank Ludivine Garrier (registre des cancers digestifs de Bourgogne) for her technical assistance and Jean Iwaz (Service de Biostatistique des Hospices Civils de Lyon) for the final revision of the manuscript. The EUROCARE study was supported by The Compagnia di San Paolo, Fondazione Cariplo, the Italian Ministry of Health (Ricerca Finalizzata 2009, RF-2009-1529710) and the European Commission (European Action Against Cancer, EPAAC, Joint Action No. 20102202). References: Allemani, C., Weir, H.K., Carreira, H., Harewood, R., Spika, D., Wang, X.S., Global surveillance of cancer survival 1995-2009: Analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2) (2015) Lancet, 385, pp. 977-1010; Cottet, V., Bouvier, V., Rollot, F., Jooste, V., Bedenne, L., Faivre, J., Incidence and patterns of late recurrences in rectal cancer patients (2015) Ann Surg Oncol, 22, pp. 520-527; Crocetti, E., Bossard, N., Uhry, Z., Roche, L., Rossi, S., Capocaccia, R., Trends in net survival from 15 cancers in six European Latin countries: The SUDCAN population-based study material (2016) Eur J Cancer Prev, 25, pp. S3-S8; Dahlberg, M., Glimelius, B., Påhlman, L., Improved survival and reduction in local failure rates after preoperative radiotherapy: Evidence for the generalizability of the results of Swedish Rectal Cancer Trial (1999) Ann Surg, 229, pp. 493-497; De Angelis, R., Francisci, S., Baili, P., Marchesi, F., Roazzi, P., Belot, A., The EUROCARE-4 database on cancer survival in Europe: Data standardisation, quality control and methods of statistical analysis (2009) Eur J Cancer, 45, pp. 909-930; De Angelis, R., Sant, M., Coleman, M.P., Francisci, S., Baili, P., Pierannunzio, D., Cancer survival in Europe 1999-2007 by country and age: Results of EUROCARE-5 - A population-based study (2014) Lancet Oncol, 15, pp. 23-34; De Gramont, A., Bosset, J.F., Milan, C., Rougier, P., Bouché, O., Etienne, P.L., Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study (1997) J Clin Oncol, 15, pp. 808-815; Desgrippes, R., Bouvier, V., Delafosse, P., Robaszkiewicz, M., Molinié, F., Trétarre, B., Management of rectal cancer in France in a well-defined population (2014) Eur J Gastroenterol Hepatol, 26, pp. 743-747; Ferlay, J., Soerjomataram, I., Ervik, M., Dikshit, R., Eser, S., Mathers, C., (2013) GLOBOCAN 2012 v10, Cancer Incidence and Mortality Worldwide: IARC Cancerbase No 11, , http://globocan.iarc.fr, Lyon, France: International Agency for Research on Cancer. [Accessed 9 September 2016]; Kapiteijn, E., Marijnen, C.A., Nagtegaal, I.D., Putter, H., Steup, W.H., Wiggers, T., Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer (2001) N Engl J Med, 345, pp. 638-646; Minicozzi, P., Bouvier, A.M., Faivre, J., Sant, M., Management of rectal cancers in relation to treatment guidelines: A population-based study comparing Italian and French patients (2014) Dig Liver Dis, 46, pp. 645-651; Mitry, E., Bouvier, A.M., Esteve, J., Faivre, J., Benefit of operative mortality reduction on colorectal cancer survival (2002) Br J Surg, 89, pp. 1557-1562; Morris, E.J., Taylor, E.F., Thomas, J.D., Quirke, P., Finan, P.J., Coleman, M.P., Thirty-day postoperative mortality after colorectal cancer surgery in England (2011) Gut, 60, pp. 806-813; Perme, M.P., Stare, J., Estève, J., On estimation in relative survival (2012) Biometrics, 68, pp. 113-120; Quipourt, V., Jooste, V., Cottet, V., Faivre, J., Bouvier, A.M., Comorbidities alone do not explain the undertreatment of colorectal cancer in older adults: A French population-based study (2011) J Am Geriatr Soc, 59, pp. 694-698; Smedh, K., Olsson, L., Johansson, H., Aberg, C., Andersson, M., Reduction of postoperative morbidity and mortality in patients with rectal cancer following the introduction of a colorectal unit (2001) Br J Surg, 88, pp. 273-277; Uhry, Z., Bossard, N., Remontet, L., Iwaz, J., Roche, L., New insights into survival trend analyses in cancer population-based studies: The SUDCAN methodology (2016) Eur J Cancer Prev, 25, pp. S9-S15

PY - 2017

Y1 - 2017

N2 - Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare the net survival from rectal cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000-2004 using the Pohar-Perme estimator. For trend analyses, the study-period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain, and Switzerland and from 2000 to 2004 in Belgium and Portugal. These analyses were carried out using a flexible excess rate modeling strategy. There were some differences between countries in age-standardized net survivals (2000-2004). The 5-year survival ranged from 55% (Portugal) to 62% (Belgium). There was an increase in agestandardized survival rates between 1992 and 2004 as observed at 1 and 5 years. This increase was observed in the 60 and 70-year age groups, but was less marked in the 80-year age group. This was related to a decrease in the excess mortality rates between 1992 and 2004, until ∼24 months after diagnosis in France and Switzerland, whereas it was continuous over the entire study period in Italy and Spain. Considerable improvements in survival from rectal cancer have been achieved. Further improvements are expected through better adherence to the guidelines and the implementation of mass screening. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

AB - Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare the net survival from rectal cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000-2004 using the Pohar-Perme estimator. For trend analyses, the study-period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain, and Switzerland and from 2000 to 2004 in Belgium and Portugal. These analyses were carried out using a flexible excess rate modeling strategy. There were some differences between countries in age-standardized net survivals (2000-2004). The 5-year survival ranged from 55% (Portugal) to 62% (Belgium). There was an increase in agestandardized survival rates between 1992 and 2004 as observed at 1 and 5 years. This increase was observed in the 60 and 70-year age groups, but was less marked in the 80-year age group. This was related to a decrease in the excess mortality rates between 1992 and 2004, until ∼24 months after diagnosis in France and Switzerland, whereas it was continuous over the entire study period in Italy and Spain. Considerable improvements in survival from rectal cancer have been achieved. Further improvements are expected through better adherence to the guidelines and the implementation of mass screening. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

KW - Cancer registries

KW - Europe

KW - Excess mortality rates

KW - Net survival

KW - Rectal cancer

KW - Trends analysis

KW - adolescent

KW - adult

KW - aged

KW - Article

KW - Belgium

KW - cancer survival

KW - female

KW - follow up

KW - France

KW - groups by age

KW - human

KW - Italy

KW - major clinical study

KW - male

KW - multicenter study

KW - population research

KW - Portugal

KW - practice guideline

KW - priority journal

KW - rectum cancer

KW - Spain

KW - survival rate

KW - Switzerland

KW - very elderly

KW - epidemiology

KW - factual database

KW - health survey

KW - middle aged

KW - mortality

KW - procedures

KW - rectum tumor

KW - register

KW - trends

KW - young adult

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Databases, Factual

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Population Surveillance

KW - Rectal Neoplasms

KW - Registries

KW - Survival Rate

KW - Young Adult

U2 - 10.1097/CEJ.0000000000000305

DO - 10.1097/CEJ.0000000000000305

M3 - Article

VL - 26

SP - S48-S55

JO - European Journal of Cancer Prevention

JF - European Journal of Cancer Prevention

SN - 0959-8278

IS - suppl 1

ER -