Trichoblastoma: Is a clinical or dermoscopic diagnosis possible?

G. Ghigliotti, E. De Col, A. Parodi, C. Bombonato, G. Argenziano

Research output: Contribution to journalArticlepeer-review


Background: Trichoblastoma is a rare benign skin tumour that must be differentiated from basal cell carcinoma for its benign course and favourable outcome. Objectives: To describe clinical and dermoscopic features of solitary primitive trichoblastoma and to compare them with trichoblastic basal cell carcinoma (tBCC). Methods: Digital dermoscopic images of 19 trichoblastoma and 19 tBCC were compared and reviewed by a dermatologist experienced in dermoscopy. Results: The most striking dermoscopic difference between trichoblastoma and tBCC was the presence of blue-grey globules and blue-grey ovoid nests that were found to be more frequent but not exclusive of tBCC. Arborizing vessels were found both in trichoblastoma and tBCC, with a lower frequency in the latter. Conclusion: Histology remains the gold standard to differentiate trichoblastoma from tBCC.

Original languageEnglish
JournalJournal of the European Academy of Dermatology and Venereology
Publication statusAccepted/In press - 2016

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases


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