Tricuspid valve replacement with mechanical prostheses: Long-term results

Andrea Garatti, Alberto Canziani, Eugenio Mossuto, Piervincenzo Gagliardotto, Francesco Innocente, Livio Corain, Alessandro Frigiola, Lorenzo Menicanti

Research output: Contribution to journalArticlepeer-review


Background and aim of the study: Historically, tricuspid valve replacement (TVR) has been associated with high mortality and morbidity, and current knowledge in the long-term outcome of TVR is limited. The study aim was to review the authors' experience from a consecutive series of patients. Methods: Between January 1990 and December 2005, a total of 43 patients (seven males, 36 females; mean age 52±14 years) underwent TVR. The etiology was rheumatic in 33 patients (77%) and degenerative disease in 10 (22%). Thirty-six patients (84%) were in NYHA class III or IV. Thirty-four patients (79%) underwent redo procedures; all patients underwent TVR with a mechanical prosthesis. Results: The overall operative mortality was 16% (n = 7). Of the 36 survivors, nine (25%) died during follow up. The Kaplan-Meier survival at 2.5, 5, and 10 years was 78%, 70%, and 58%, respectively. Five patients (14%) underwent reoperation during follow up (three for tricuspid valve thrombosis) and all five survived the reoperation. Freedom from reoperation at five and 10 years was 90% and 74%, respectively. On permutation test analysis, older age, liver congestion and redo surgery were found to be the major determinants of long-term mortality. Conclusion: TVR carries a higher short- and longterm mortality when compared to left-heart valve surgery. A timely referral before the development of end-stage cardiac impairment might determine a further improvement in outcome.

Original languageEnglish
Pages (from-to)194-200
Number of pages7
JournalJournal of Heart Valve Disease
Issue number2
Publication statusPublished - Mar 2010

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Tricuspid valve replacement with mechanical prostheses: Long-term results'. Together they form a unique fingerprint.

Cite this