Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos

Ilaria Stanghellini, Geppino Falco, Sung Lim Lee, Manuela Monti, Minoru S H Ko

Research output: Contribution to journalArticle

Abstract

We describe the identification and characterization of Trim43a, Trim43b, and Trim43c genes, whose expression are restricted to preimplantation stages and peak at the 8-cell to morula stage. We identified a 5 kb DNA fragment that covers upstream region of Trim43a as a putative promoter, which can drive the expression of mStrawberry fluorescent protein in a manner similar to endogenous Trim43 genes. Trim43 genes will be useful stage-specific markers for the study of preimplantation embryos.

Original languageEnglish
Pages (from-to)595-602
Number of pages8
JournalGene Expression Patterns
Volume9
Issue number8
DOIs
Publication statusPublished - Dec 2009

Keywords

  • 8-Cell
  • Asymmetric PCR
  • Fluorescent proteins
  • Gene expression
  • Morula
  • Mouse preimplantation
  • Promoter analysis

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Developmental Biology

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