Triton WR 1339: Effect on the reticulo-endothelial system (RES) activity in tumor-bearing mice

G. Franchi, I. Reyers Degli Innocenti, S. Standen, S. Garattini

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The reticulo-endothelial system (RES) activity in normal and in intracerebral Sarcoma 180-bearing mice was investigated after acute or subchronic treatment with the non-ionic surface-active agent: Triton WR 1339 (TWR). While the single treatment is ineffective, the subchronic treatment markedly raises the phagocytic index not only in normal mice but also in tumor-bearing animals where the RES is depressed by the presence of disseminating cancer cells. A possible relation between the RES stimulatory capacity and the antimetastatic effect exerted by TWR is envisaged.

Original languageEnglish
Pages (from-to)487-490
Number of pages4
JournalEuropean Journal of Cancer (1965)
Volume9
Issue number7
DOIs
Publication statusPublished - 1973

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Sarcoma 180
Surface-Active Agents
Neoplasms
tyloxapol

ASJC Scopus subject areas

  • Oncology
  • Medicine(all)

Cite this

Triton WR 1339 : Effect on the reticulo-endothelial system (RES) activity in tumor-bearing mice. / Franchi, G.; Innocenti, I. Reyers Degli; Standen, S.; Garattini, S.

In: European Journal of Cancer (1965), Vol. 9, No. 7, 1973, p. 487-490.

Research output: Contribution to journalArticle

Franchi, G. ; Innocenti, I. Reyers Degli ; Standen, S. ; Garattini, S. / Triton WR 1339 : Effect on the reticulo-endothelial system (RES) activity in tumor-bearing mice. In: European Journal of Cancer (1965). 1973 ; Vol. 9, No. 7. pp. 487-490.
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