Abstract
The presence of human trophoblast cells in maternal blood was investigated by the use offlow cytometry and a monoclonal antibody reacting against a specific antigen present on the surface of these cells. Three types of cells derived from the placenta could be detected in the peripheral blood obtained from women between 6 weeks' gestation and term. One group of cells were polynucleated, a second group were diploid, and a third consisted of anucleate cells derived from the syncytiotrophoblast. These cells should be suitable for prenatal diagnosis of chromosomal and biochemical abnormalities.
Original language | English |
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Pages (from-to) | 841-843 |
Number of pages | 3 |
Journal | Lancet |
Volume | 324 |
Issue number | 8407 |
DOIs | |
Publication status | Published - Oct 13 1984 |
ASJC Scopus subject areas
- Medicine(all)