Troponin i measured with a high sensitivity immunoassay is significantly increased after a half marathon run

Giuseppe Lippi, Federico Schena, Mariella Dipalo, Martina Montagnana, Gian L. Salvagno, Rosalia Aloe, Gian C. Guidi

Research output: Contribution to journalArticle

Abstract

Only a few studies have assessed the kinetics of cardiac troponins after endurance exercise by using the novel high-sensitive (HS) immunoassays. These were based on the measurement of HS-TroponinT (TnT), but not HS-Troponin I (TnI), and exclusively involved marathon or ultra-marathon contests. TnI was measured in 17 healthy trained Caucasian males performing a 21 km, half-marathon, with the conventional AccuTnI and the HS-AccuTnI immunoassays. The concentration of HS-AccuTnI significantly increased from the mean baseline value of 2.9 ng/L (Interquartile range [IQR], 2.4 4.3 ng/L) to 4.8 (IQR, 3.05.7 ng/L) after the run (p 0.002), 9.0 ng/L (IQR, 5.815.3 ng/L) at 3h (p

Original languageEnglish
Pages (from-to)467-470
Number of pages4
JournalScandinavian Journal of Clinical and Laboratory Investigation
Volume72
Issue number6
DOIs
Publication statusPublished - Oct 2012

Keywords

  • Cardiac biomarkers
  • Marathon
  • Physical exercise
  • Sport
  • Troponin

ASJC Scopus subject areas

  • Clinical Biochemistry

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