Tryptamine levels are low in plasma of chronic migraine and chronic tension-type headache

Giovanni D’Andrea, Domenico D’Amico, Gennaro Bussone, Andrea Bolner, Marco Aguggia, Maria Gabriella Saracco, Elisabetta Galloni, Valentina De Riva, Antonello D’Arrigo, Davide Colavito, Alberta Leon, Francesco Perini

Research output: Contribution to journalArticle

Abstract

The primary aim of this study (TA-CH, Tryptophan Amine in Chronic Headache) was to investigate a possible role of tryptophan (TRP) metabolism in chronic migraine (CM) and chronic tension-type headache (CTTH). It is not known if TRP metabolism plays any role in CM and/or CTTH. Plasma levels of serotonin (5-HT), 5-hydroxyindolacetic acid (5-HIAA), metabolite of 5-HT, and tryptamine (TRY) were tested in 73 patients with CM, 15 patients with CTTH and 37 control subjects. Of these, plasmatic TRY was significantly lower in CM (p 

Original languageEnglish
Pages (from-to)1941-1945
Number of pages5
JournalNeurological Sciences
Volume35
Issue number12
DOIs
Publication statusPublished - Nov 25 2014

Keywords

  • Chronic migraine
  • Tryptamine
  • Tryptophan metabolism

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)

Fingerprint Dive into the research topics of 'Tryptamine levels are low in plasma of chronic migraine and chronic tension-type headache'. Together they form a unique fingerprint.

  • Cite this

    D’Andrea, G., D’Amico, D., Bussone, G., Bolner, A., Aguggia, M., Saracco, M. G., Galloni, E., De Riva, V., D’Arrigo, A., Colavito, D., Leon, A., & Perini, F. (2014). Tryptamine levels are low in plasma of chronic migraine and chronic tension-type headache. Neurological Sciences, 35(12), 1941-1945. https://doi.org/10.1007/s10072-014-1867-5