Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice

Amelia Licari; Dietmar Fuchs; Gianluigi Marseglia; Giorgio Ciprandi

doi:10.1186/s13052-019-0699-6

Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice

Amelia Licari, Dietmar Fuchs, Gianluigi Marseglia, Giorgio Ciprandi

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p

Original language	English
Pages (from-to)	114
Number of pages	1
Journal	Italian Journal of Pediatrics
Volume	45
Issue number	1
DOIs	https://doi.org/10.1186/s13052-019-0699-6
Publication status	Published - Aug 28 2019

Keywords

Asthma
Children
Kynurenine
Neopterin
Tryptophan
Adolescent
Asthma/*metabolism
Case-Control Studies
Child
Cross-Sectional Studies
Female
Humans
Male
Metabolic Networks and Pathways
Neopterin/*metabolism
Tryptophan/*metabolism

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title = "Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice",

abstract = "Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p ",

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author = "Amelia Licari and Dietmar Fuchs and Gianluigi Marseglia and Giorgio Ciprandi",

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AU - Licari, Amelia

AU - Fuchs, Dietmar

AU - Marseglia, Gianluigi

AU - Ciprandi, Giorgio

PY - 2019/8/28

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N2 - Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p

AB - Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p

KW - Asthma

KW - Children

KW - Kynurenine

KW - Neopterin

KW - Tryptophan

KW - Adolescent

KW - Asthma/metabolism

KW - Case-Control Studies

KW - Child

KW - Cross-Sectional Studies

KW - Female

KW - Humans

KW - Male

KW - Metabolic Networks and Pathways

KW - Neopterin/metabolism

KW - Tryptophan/metabolism

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DO - 10.1186/s13052-019-0699-6

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JO - Italian Journal of Pediatrics

JF - Italian Journal of Pediatrics

SN - 1720-8424

IS - 1

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Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice

Abstract

Keywords

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