Abstract
Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p
Original language | English |
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Pages (from-to) | 114 |
Number of pages | 1 |
Journal | Italian Journal of Pediatrics |
Volume | 45 |
Issue number | 1 |
DOIs | |
Publication status | Published - Aug 28 2019 |
Keywords
- Asthma
- Children
- Kynurenine
- Neopterin
- Tryptophan
- Adolescent
- Asthma/*metabolism
- Case-Control Studies
- Child
- Cross-Sectional Studies
- Female
- Humans
- Male
- Metabolic Networks and Pathways
- Neopterin/*metabolism
- Tryptophan/*metabolism