Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice

Amelia Licari, Dietmar Fuchs, Gianluigi Marseglia, Giorgio Ciprandi

Research output: Contribution to journalArticlepeer-review


Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopterin were measured in asthmatic children (121, 71 males, 50 females, mean age 11.6 + 3.2 years) and well-matched healthy controls (63, 32 males, 31 females, mean age 10.7 + 2.6 years). Tryptophan, kynurenine, and neopterin levels were significantly higher in asthmatic children than in healthy controls (p 
Original languageEnglish
Pages (from-to)114
Number of pages1
JournalItalian Journal of Pediatrics
Issue number1
Publication statusPublished - Aug 28 2019


  • Asthma
  • Children
  • Kynurenine
  • Neopterin
  • Tryptophan
  • Adolescent
  • Asthma/*metabolism
  • Case-Control Studies
  • Child
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Metabolic Networks and Pathways
  • Neopterin/*metabolism
  • Tryptophan/*metabolism


Dive into the research topics of 'Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice'. Together they form a unique fingerprint.

Cite this