In 1997 a novel virus in the serum of a patient with acute post-transfusion hepatitis of non A-G etiology was identified. This agent was designed TT virus (TTV). It produces persistent viremia and no disease, but the mechanism of its persistence is poorly understood. In the present study mRNA expression of antiviral proteins as MxA, 2′ 5′ OAS, anti-apopotic protein, cytokines IL- 28, IL- 29 and IFN are examined in a subject affected by B lymphoma and positive for TTV DNA and RNA in this cellular subset, and in BJAB and Dohh2 cell lines.
|Number of pages||10|
|Journal||International Journal of Immunopathology and Pharmacology|
|Publication status||Published - Apr 2007|
- Antiviral protein production
- TTV infection
ASJC Scopus subject areas