Tuberoinfundibular dopaminergic function in Parkinson's disease

M. Franceschi, M. Camerlingo, L. Perego, E. Bottacchi, G. Truci, A. Mamoli

Research output: Contribution to journalArticlepeer-review


A deficit of nigrostriatal, mesocortical and mesolimbic dopamine systems in Parkinson's disease is well known. We know less about the involvement of tuberoinfundibular dopamine (TID) systems. In untreated (naive or wash-out) men with Parkinson's disease, we studied TID function through basal and stimulated plasma levels of growth hormone, prolactin and thyrotropin. Only minor abnormalities in prolactin responses to thyrotropin-releasing hormone were found, probably reflecting denervation hypersensitivity. TID function is preserved in men with Parkinson's disease.

Original languageEnglish
Pages (from-to)117-119
Number of pages3
JournalEuropean Neurology
Issue number3
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Clinical Neurology


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