Abstract
The purpose of this study was to assess the prognostic and predictive value of tumor-infiltrating lymphocytes (TILs) in the triple-negative breast cancer (TNBC) cohort of the phase III IBCSG trial 22-00, comparing low-dose oral ‘metronomic’ cyclophosphamide-methotrexate maintenance chemotherapy (CM-maintenance) to no-CM-maintenance in early breast cancer. TILs were evaluated in full-face hematoxylin-and-eosin-stained sections of tumor samples confirmed centrally as TNBC (
Original language | English |
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Pages (from-to) | 323-331 |
Number of pages | 9 |
Journal | Breast Cancer Research and Treatment |
Volume | 158 |
Issue number | 2 |
DOIs | |
Publication status | Published - Jul 1 2016 |
Keywords
- Breast cancer
- Low-dose maintenance chemotherapy
- Prognosis
- Triple negative
- Tumor-infiltrating lymphocytes
ASJC Scopus subject areas
- Oncology
- Cancer Research