Tumor necrosis factor in plasma and peritoneal fluid of women with and without endometriosis

Paolo Vercellini, Fabrizio De Benedetti, Edoardo Rossi, Alberto Colombo, Laura Trespidi, Pier Giorgio Crosignani

Research output: Contribution to journalArticle

Abstract

To determine whether in vivo levels of tumor necrosis factor a in plasma and peritoneal fluid differ in infertile subjects with and without endometriosis, peripheral blood and peritoneal fluid samples were collected in 94 women undergoing laparoscopy for infertility. Quantitative determinations of tumor necrosis factor a were performed by an enzyme immunoassay test. Tumor necrosis factor a levels were below the detection limit (10 pg/ml) in plasma and peritoneal fluid of 42 (91%) and 30 (90%) patients with endometriosis and 40 (83%) and 31 (91%) subjects without the disease, respectively. In our series. plasma and tumor necrosis factor a levels were not different in infertile women with and without endometriosis.

Original languageEnglish
Pages (from-to)39-41
Number of pages3
JournalGynecologic and Obstetric Investigation
Volume36
Issue number1
DOIs
Publication statusPublished - 1993

Keywords

  • Endometriosis
  • Infertility
  • Tumor necrosis factor

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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