Tumor suppression by DNA base excision repair

Research output: Contribution to journalArticlepeer-review


Base excision repair (BER) is the main pathway for repair of endogenous DNA damage. It was expected that different tumor types could derive from BER defects but to date this link is elusive. In vitro and molecular epidemiology studies may be used to unravel this issue.

Original languageEnglish
Pages (from-to)727-743
Number of pages17
JournalMini-Reviews in Medicinal Chemistry
Issue number7
Publication statusPublished - Jul 2007


  • 8-oxoguanine
  • Chemotherapy
  • DNA base excision repair
  • Glycosylase
  • In vitro neoplastic transformation
  • Molecular epidemiology
  • Mutation
  • Oxidative DNA damage

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Chemistry(all)
  • Pharmacology


Dive into the research topics of 'Tumor suppression by DNA base excision repair'. Together they form a unique fingerprint.

Cite this