Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire

assessment of reliability and validity

Sevim Bavbek, Seçil Kepil Özdemir, Beyza Doğanay Erdoğan, Işıl Karaboğa, Suna Büyüköztürk, Aslı Gelincik, İnsu Yılmaz, Özlem Göksel, Adile Berna Dursun, Gül Karakaya, Ali Fuat Kalyoncu, Ferhan Özşeker, Gülden Paşaoğlu Karakış, Ferda Öner Erkekol, Gözde Köycü, Metin Keren, Ilaria Baiardini, Antonino Romano

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: The first disease-specific quality-of-life questionnaire in patients with drug hypersensitivity, Drug Hypersensitivity Quality of Life Questionnaire (DrHy-Q), was developed and validated recently. The aim of this study was to assess validity, reliability and responsiveness to interventions of the Turkish version of the DrHy-Q. Methods: The Turkish version of the DrHy-Q was administered to prospectively enrolled 736 patients with drug hypersensitivity from ten allergy units. To assess validity, all patients completed the validated Turkish version of Psychological General Well-Being Index (PGWBI). For test–retest reliability, 182 patients completed the DrHy-Q 1 week after the first questionnaire administration without any intervention. Responsiveness was assessed on 97 patients who had a DrHy-Q recorded at a follow-up visit after the intervention. Results: The internal consistency and test–retest reliability of the scale were adequate (Cronbach’s alpha = 0.934, intra-class correlation coefficient = 0.783). The DrHy-Q scores showed weak negative correlations with the PGWBI total and domain scores (r = − 0.378 to −0.254, p  0.05). The baseline DrHy-Q scores were significantly higher than the post-intervention scores (p = 0.008). Conclusion: The Turkish version of DrHy-Q is reliable and valid for evaluating quality of life in patients with drug hypersensitivity, and it appeared responsive to interventions.

Original languageEnglish
Pages (from-to)101-109
Number of pages9
JournalQuality of Life Research
Volume25
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Drug Hypersensitivity
Reproducibility of Results
Quality of Life
Psychology
Surveys and Questionnaires
Hypersensitivity

Keywords

  • Disease-specific questionnaires
  • Drug allergy
  • Drug hypersensitivity
  • Quality of life

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Bavbek, S., Kepil Özdemir, S., Doğanay Erdoğan, B., Karaboğa, I., Büyüköztürk, S., Gelincik, A., ... Romano, A. (2016). Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire: assessment of reliability and validity. Quality of Life Research, 25(1), 101-109. https://doi.org/10.1007/s11136-015-1051-2

Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire : assessment of reliability and validity. / Bavbek, Sevim; Kepil Özdemir, Seçil; Doğanay Erdoğan, Beyza; Karaboğa, Işıl; Büyüköztürk, Suna; Gelincik, Aslı; Yılmaz, İnsu; Göksel, Özlem; Dursun, Adile Berna; Karakaya, Gül; Kalyoncu, Ali Fuat; Özşeker, Ferhan; Paşaoğlu Karakış, Gülden; Öner Erkekol, Ferda; Köycü, Gözde; Keren, Metin; Baiardini, Ilaria; Romano, Antonino.

In: Quality of Life Research, Vol. 25, No. 1, 01.01.2016, p. 101-109.

Research output: Contribution to journalArticle

Bavbek, S, Kepil Özdemir, S, Doğanay Erdoğan, B, Karaboğa, I, Büyüköztürk, S, Gelincik, A, Yılmaz, İ, Göksel, Ö, Dursun, AB, Karakaya, G, Kalyoncu, AF, Özşeker, F, Paşaoğlu Karakış, G, Öner Erkekol, F, Köycü, G, Keren, M, Baiardini, I & Romano, A 2016, 'Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire: assessment of reliability and validity', Quality of Life Research, vol. 25, no. 1, pp. 101-109. https://doi.org/10.1007/s11136-015-1051-2
Bavbek S, Kepil Özdemir S, Doğanay Erdoğan B, Karaboğa I, Büyüköztürk S, Gelincik A et al. Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire: assessment of reliability and validity. Quality of Life Research. 2016 Jan 1;25(1):101-109. https://doi.org/10.1007/s11136-015-1051-2
Bavbek, Sevim ; Kepil Özdemir, Seçil ; Doğanay Erdoğan, Beyza ; Karaboğa, Işıl ; Büyüköztürk, Suna ; Gelincik, Aslı ; Yılmaz, İnsu ; Göksel, Özlem ; Dursun, Adile Berna ; Karakaya, Gül ; Kalyoncu, Ali Fuat ; Özşeker, Ferhan ; Paşaoğlu Karakış, Gülden ; Öner Erkekol, Ferda ; Köycü, Gözde ; Keren, Metin ; Baiardini, Ilaria ; Romano, Antonino. / Turkish version of the Drug Hypersensitivity Quality of Life Questionnaire : assessment of reliability and validity. In: Quality of Life Research. 2016 ; Vol. 25, No. 1. pp. 101-109.
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AU - Bavbek, Sevim

AU - Kepil Özdemir, Seçil

AU - Doğanay Erdoğan, Beyza

AU - Karaboğa, Işıl

AU - Büyüköztürk, Suna

AU - Gelincik, Aslı

AU - Yılmaz, İnsu

AU - Göksel, Özlem

AU - Dursun, Adile Berna

AU - Karakaya, Gül

AU - Kalyoncu, Ali Fuat

AU - Özşeker, Ferhan

AU - Paşaoğlu Karakış, Gülden

AU - Öner Erkekol, Ferda

AU - Köycü, Gözde

AU - Keren, Metin

AU - Baiardini, Ilaria

AU - Romano, Antonino

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