Twenty-four-hour spectral analysis of heart rate variability in congestive heart failure secondary to coronary artery disease

Giancarlo Casolo, Enrico Balli, Antonio Fazi, Cesare Gori, Angelo Freni, Gianfranco Gensini

Research output: Contribution to journalArticlepeer-review

Abstract

It is well known that heart rate (HR) fluctuates in time and that this variation is closely related to changes in the neural activity to the heart.1,2 Therefore, HR variability represents a noninvasive parameter for studying the autonomic control to the heart. Recently, it has been shown that HR variability is a powerful independent prognostic factor in patients with coronary artery disease3 and a low HR variability count has been found to be related to sudden death.4 Spectrum analysis of HR may provide further information, since HR variability possesses 2 major components that have been shown to relate to different patterns of neural control to the heart.5,6 Patients with congestive heart failure (CHF) have a complex abnormality of the autonomic control to the heart7 that also affects some HR characteristics.8 These abnormalities may be determined either by a selective reduction of the vagal outflow to the heart or by a more complex abnormality. This investigation was undertaken to evaluate the components of HR variability in normal persons and patients with CHF, and their 24-hour behavior.

Original languageEnglish
Pages (from-to)1154-1158
Number of pages5
JournalThe American Journal of Cardiology
Volume67
Issue number13
DOIs
Publication statusPublished - May 15 1991

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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