Two novel alleles at HLA-B locus identified in two volunteer bone marrow donors by sequence-based typing

S. Frison, E. Longhi, M. Mantovani, A. Malagoli, A. De Giuli, G. Piccolo, F. Poli

Research output: Contribution to journalArticle

Abstract

Summary: Two novel human leucocyte antigen (HLA) class I alleles have been identified in two Italian individuals. HLA-B*27:07:02 is identical to HLA-B*27:07:01 except for a nucleotide substitution at position 846 (A->G) resulting in a silent mutation. HLA-B*35:206 differs from the most similar allele, HLA-B*35:08:01, because of a single base mutation at position 149 (G->C) causing an aminoacidic change at codon 26 from Gly to Ala.

Original languageEnglish
Pages (from-to)328-330
Number of pages3
JournalInternational Journal of Immunogenetics
Volume40
Issue number4
DOIs
Publication statusPublished - 2013

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Immunology
  • Genetics(clinical)
  • Medicine(all)

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