Two-year clinical follow-up of children and adolescents after percutaneous transluminal angioplasty for renovascular hypertension

E. Casalini, S. Sfondrini, F. Fossali

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Rationale and Objectives. Two percent of children have hypertension. For those younger than 10 years of age, there is a high probability that hypertension is secondary. The purpose of this study was to evaluate the merits of percutaneous transluminal angioplasty (PTA) in the treatment of childhood renovascular hypertension (RVH) in light of the results previously obtained by the authors and to evaluate their stability at 2-year follow-up. Methods. The positive response of peripheral renin plasma levels to a single dose of captopril was used as a criterion for selecting 36 patients between 4 and 15 years of age with renovascular hypertension. All underwent angiography; in most patients, PTA was performed in the same session. A 2-year follow-up study was conducted. Results. In the 36 patients considered for RVH screening, PTA was successful in 34 of 36 patients (94%). Four of these patients had neurofibromatosis. The high success rate was confirmed in the 2-year follow-up study: 34 patients continue to be normotensive. Conclusions. Percutaneous transluminal angioplasty treatment of pediatric patients with hypertension has proved to be an effective and valuable method when the cause of renal artery stenosis is fibromuscular dysplasia, and the long-term results were sufficient to suggest the use of this technique in patients with neurofibromatosis as well.

Original languageEnglish
Pages (from-to)40-43
Number of pages4
JournalInvestigative Radiology
Volume30
Issue number1
Publication statusPublished - 1995

Fingerprint

Renovascular Hypertension
Angioplasty
Neurofibromatoses
Hypertension
Fibromuscular Dysplasia
Renal Artery Obstruction
Captopril
Renin
Angiography
Pediatrics
Therapeutics

Keywords

  • Angiography
  • Digital subtraction (DSA)
  • Hypertension in children
  • Percutaneous transluminal angioplasty
  • Renal PTA in children
  • Renovascular hypertension

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Two-year clinical follow-up of children and adolescents after percutaneous transluminal angioplasty for renovascular hypertension. / Casalini, E.; Sfondrini, S.; Fossali, F.

In: Investigative Radiology, Vol. 30, No. 1, 1995, p. 40-43.

Research output: Contribution to journalArticle

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