Riparazione della membrana timpanica con acido ialuronico

Translated title of the contribution: Tympanic membrane repair with hyaluronic-acid. Personal technique

C. Guastella, C. Borsi, S. Gibelli, F. Klinger, M. Mantovani

Research output: Contribution to journalArticlepeer-review


Background. Tympanic membrane laceration is anything but rare in every- day ENT practice. Hyaluronic-acid has been recently shown to be an effective tool for tympanic membrane reconstruction. Methods. Forty consecutive patients with tympanic membrane perforations (31 traumatic and 9 due to chronic otitis) have been treated with hyaluronic-acid through a four steps procedure: 1) trimming of the edges of tympanic membrane perforation under local anesthesia; 2) insertion of Spongostan® pieces into middle ear; 3) covering of both sides of tympanic membrane perforation with preshaped hyaluronic-acid sheets in order to seal the hole; 4) medication of external auditory canal. Postoperative treatment required removal of the external canal medication after seven days from surgery, followed by hyaluronic-acid instillation, twice a day, for further seven days (performed by the patient). Results and conclusions. Restitutio ad integrum was detected in 80% of patients treated with hyaluronic-acid, who also showed a full recovery of the auditory function. 15% of patients had a residual small tympanic membrane perforation with the evidence of on going reparative process. The remaining 5% of patients did not show any improvement.

Translated title of the contributionTympanic membrane repair with hyaluronic-acid. Personal technique
Original languageItalian
Pages (from-to)145-150
Number of pages6
Issue number4
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Otorhinolaryngology


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