Type 2 diabetes mellitus treatment habits in a specialized care setting: The START-DIAB study

Sandro Gentile, Antonio Ceriello, Giuseppe Pipicelli, Felice Strollo, START DIAB Study Group

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

BACKGROUND: Early optimized lifestyle and medication treatment can reduce the burden of type 2 diabetes mellitus (T2DM). Although Diabetologists take care of most Italian people withT2DMand are the only allowed to prescribe innovative drugs, still half T2DM patients are poorly controlled. AIMS: To verify specialists’ propensity to reach individualized glycemic goals by treating to target newly referred people with T2DM having HbA1c levels >7% (>53 mmol/mol). MATERIALS AND METHODS: 2536 poorly controlled, orally treated T2DM from all over Italy were evaluated and followed up for 6 months for appropriate nutritional and pharmacologic treatment in a specialized setting and diabetologists filled in a questionnaire on supposed reasons behind patients’ poor metabolic control and on their own therapeutic choices. RESULTS: At the first visit only 71.8% people underwent slight treatment adaptations (through a slight reduction of secretagogue utilization accompanied, to a lesser extent, by some increase in incretin prescription (from 13.4% to 33.5%; p < 001) and by de novo insulin administration (3.8%). Specialists stated three major reasons for poor control as observed at referral. Two of them, i.e. disease per se (secondary failure) and patients’ attitude (poor adherence), were high-rated, while the other one, addressing clinicians’ responsibility, was only marginally accounted for despite most diabetes specialists still going on with secretagogues all the time. Detailed results are provided within the text.

Original languageEnglish
Pages (from-to)165-179
Number of pages15
JournalMediterranean Journal of Nutrition and Metabolism
Volume10
Issue number2
DOIs
Publication statusPublished - Jan 1 2017

Fingerprint

noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
Habits
secretin
Incretins
glycohemoglobin
Therapeutics
Italy
drug therapy
lifestyle
Prescriptions
diabetes
Life Style
insulin
Referral and Consultation
questionnaires
Insulin
drugs
therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Food Science
  • Nutrition and Dietetics

Cite this

Type 2 diabetes mellitus treatment habits in a specialized care setting : The START-DIAB study. / Gentile, Sandro; Ceriello, Antonio; Pipicelli, Giuseppe; Strollo, Felice; START DIAB Study Group.

In: Mediterranean Journal of Nutrition and Metabolism, Vol. 10, No. 2, 01.01.2017, p. 165-179.

Research output: Contribution to journalArticle

Gentile, Sandro ; Ceriello, Antonio ; Pipicelli, Giuseppe ; Strollo, Felice ; START DIAB Study Group. / Type 2 diabetes mellitus treatment habits in a specialized care setting : The START-DIAB study. In: Mediterranean Journal of Nutrition and Metabolism. 2017 ; Vol. 10, No. 2. pp. 165-179.
@article{02eef3ef2de944fa968af9481d1b0059,
title = "Type 2 diabetes mellitus treatment habits in a specialized care setting: The START-DIAB study",
abstract = "BACKGROUND: Early optimized lifestyle and medication treatment can reduce the burden of type 2 diabetes mellitus (T2DM). Although Diabetologists take care of most Italian people withT2DMand are the only allowed to prescribe innovative drugs, still half T2DM patients are poorly controlled. AIMS: To verify specialists’ propensity to reach individualized glycemic goals by treating to target newly referred people with T2DM having HbA1c levels >7{\%} (>53 mmol/mol). MATERIALS AND METHODS: 2536 poorly controlled, orally treated T2DM from all over Italy were evaluated and followed up for 6 months for appropriate nutritional and pharmacologic treatment in a specialized setting and diabetologists filled in a questionnaire on supposed reasons behind patients’ poor metabolic control and on their own therapeutic choices. RESULTS: At the first visit only 71.8{\%} people underwent slight treatment adaptations (through a slight reduction of secretagogue utilization accompanied, to a lesser extent, by some increase in incretin prescription (from 13.4{\%} to 33.5{\%}; p < 001) and by de novo insulin administration (3.8{\%}). Specialists stated three major reasons for poor control as observed at referral. Two of them, i.e. disease per se (secondary failure) and patients’ attitude (poor adherence), were high-rated, while the other one, addressing clinicians’ responsibility, was only marginally accounted for despite most diabetes specialists still going on with secretagogues all the time. Detailed results are provided within the text.",
author = "Sandro Gentile and Antonio Ceriello and Giuseppe Pipicelli and Felice Strollo and {START DIAB Study Group}",
year = "2017",
month = "1",
day = "1",
doi = "10.3233/MNM-17160",
language = "English",
volume = "10",
pages = "165--179",
journal = "Mediterranean Journal of Nutrition and Metabolism",
issn = "1973-798X",
publisher = "IOS Press",
number = "2",

}

TY - JOUR

T1 - Type 2 diabetes mellitus treatment habits in a specialized care setting

T2 - The START-DIAB study

AU - Gentile, Sandro

AU - Ceriello, Antonio

AU - Pipicelli, Giuseppe

AU - Strollo, Felice

AU - START DIAB Study Group

PY - 2017/1/1

Y1 - 2017/1/1

N2 - BACKGROUND: Early optimized lifestyle and medication treatment can reduce the burden of type 2 diabetes mellitus (T2DM). Although Diabetologists take care of most Italian people withT2DMand are the only allowed to prescribe innovative drugs, still half T2DM patients are poorly controlled. AIMS: To verify specialists’ propensity to reach individualized glycemic goals by treating to target newly referred people with T2DM having HbA1c levels >7% (>53 mmol/mol). MATERIALS AND METHODS: 2536 poorly controlled, orally treated T2DM from all over Italy were evaluated and followed up for 6 months for appropriate nutritional and pharmacologic treatment in a specialized setting and diabetologists filled in a questionnaire on supposed reasons behind patients’ poor metabolic control and on their own therapeutic choices. RESULTS: At the first visit only 71.8% people underwent slight treatment adaptations (through a slight reduction of secretagogue utilization accompanied, to a lesser extent, by some increase in incretin prescription (from 13.4% to 33.5%; p < 001) and by de novo insulin administration (3.8%). Specialists stated three major reasons for poor control as observed at referral. Two of them, i.e. disease per se (secondary failure) and patients’ attitude (poor adherence), were high-rated, while the other one, addressing clinicians’ responsibility, was only marginally accounted for despite most diabetes specialists still going on with secretagogues all the time. Detailed results are provided within the text.

AB - BACKGROUND: Early optimized lifestyle and medication treatment can reduce the burden of type 2 diabetes mellitus (T2DM). Although Diabetologists take care of most Italian people withT2DMand are the only allowed to prescribe innovative drugs, still half T2DM patients are poorly controlled. AIMS: To verify specialists’ propensity to reach individualized glycemic goals by treating to target newly referred people with T2DM having HbA1c levels >7% (>53 mmol/mol). MATERIALS AND METHODS: 2536 poorly controlled, orally treated T2DM from all over Italy were evaluated and followed up for 6 months for appropriate nutritional and pharmacologic treatment in a specialized setting and diabetologists filled in a questionnaire on supposed reasons behind patients’ poor metabolic control and on their own therapeutic choices. RESULTS: At the first visit only 71.8% people underwent slight treatment adaptations (through a slight reduction of secretagogue utilization accompanied, to a lesser extent, by some increase in incretin prescription (from 13.4% to 33.5%; p < 001) and by de novo insulin administration (3.8%). Specialists stated three major reasons for poor control as observed at referral. Two of them, i.e. disease per se (secondary failure) and patients’ attitude (poor adherence), were high-rated, while the other one, addressing clinicians’ responsibility, was only marginally accounted for despite most diabetes specialists still going on with secretagogues all the time. Detailed results are provided within the text.

UR - http://www.scopus.com/inward/record.url?scp=85028768479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028768479&partnerID=8YFLogxK

U2 - 10.3233/MNM-17160

DO - 10.3233/MNM-17160

M3 - Article

AN - SCOPUS:85028768479

VL - 10

SP - 165

EP - 179

JO - Mediterranean Journal of Nutrition and Metabolism

JF - Mediterranean Journal of Nutrition and Metabolism

SN - 1973-798X

IS - 2

ER -