Type II odontoid fracture in elderly patients treated conservatively: is fracture healing the goal?

Giorgio Lofrese, Antonio Musio, Federico De Iure, Francesco Cultrera, Antonio Martucci, Corrado Iaccarino, Walid Ibn Essayed, Reza Ghadirpour, Franco Servadei, Michele Alessandro Cavallo, Pasquale De Bonis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: Analysis of functional outcome of elderly patients with type II odontoid fractures treated conservatively in relation to their radiological outcome. Methods: A total of 50 geriatric patients with type II odontoid fractures were treated with Aspen/Vista collars. On admission, each patient was assessed assigning ASA score, modified Rankin Scale (mRS-pre) and Charlson Comorbidity Index (CCI). From 12–15 months after treatment, functional evaluations were performed employing a second modified Rankin Scale (mRS-post) together with Neck Disability Index (NDI) and Smiley-Webster pain scale (SWPS). Radiological outcome was evaluated through dynamic cervical spine X-rays at 3 months and cervical spine CT scans 6 months after treatment. Three different conditions were identified: stable union, stable non-union and unstable non-union. Surgery was preferred whenever a fracture gap > 2 mm, an antero-posterior displacement > 5 mm, an odontoid angulation > 11° or neurological deficits occurred. Results: Among the 50 patients, 24 reached a stable union, while 26 a stable non-union. Comparing the two groups, no differences in ASA (p = 0.60), CCI (p = 0.85) and mRS-pre (p = 0.14) were noted. Similarly, no differences in mRS-post (p = 0.96), SWPS (p = 0.85) and NDI (p = 0.51) were observed between patients who reached an osseous fusion and those with a stable fibrous non-union. No effects of age, sex, ASA, mRS-pre, fracture dislocation and radiological outcome were discovered on functional outcome. At logistic regression analysis, female sex and high values of CCI emerged associated with worse NDI. Conclusions: In geriatric type II odontoid fractures, pre-injury clinical status and comorbidities overcome imaging in determining post-treatment level of function. Hard collar immobilization led to a favourable functional outcome with mRS-post, NDI and SWPS values diffusely encouraging whatever a bony union or a fibrous non-union was obtained. Graphical Abstract: These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.].

Original languageEnglish
JournalEuropean Spine Journal
DOIs
Publication statusAccepted/In press - Jan 1 2019

Fingerprint

Fracture Healing
Comorbidity
Neck
Pain
Geriatrics
Spine
Immobilization
Therapeutics
Logistic Models
Regression Analysis
X-Rays
Wounds and Injuries

Keywords

  • Collar
  • Elderly
  • Fracture
  • Healing
  • Odontoid
  • Outcome

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Lofrese, G., Musio, A., De Iure, F., Cultrera, F., Martucci, A., Iaccarino, C., ... De Bonis, P. (Accepted/In press). Type II odontoid fracture in elderly patients treated conservatively: is fracture healing the goal? European Spine Journal. https://doi.org/10.1007/s00586-019-05898-2

Type II odontoid fracture in elderly patients treated conservatively : is fracture healing the goal? / Lofrese, Giorgio; Musio, Antonio; De Iure, Federico; Cultrera, Francesco; Martucci, Antonio; Iaccarino, Corrado; Essayed, Walid Ibn; Ghadirpour, Reza; Servadei, Franco; Cavallo, Michele Alessandro; De Bonis, Pasquale.

In: European Spine Journal, 01.01.2019.

Research output: Contribution to journalArticle

Lofrese, G, Musio, A, De Iure, F, Cultrera, F, Martucci, A, Iaccarino, C, Essayed, WI, Ghadirpour, R, Servadei, F, Cavallo, MA & De Bonis, P 2019, 'Type II odontoid fracture in elderly patients treated conservatively: is fracture healing the goal?', European Spine Journal. https://doi.org/10.1007/s00586-019-05898-2
Lofrese, Giorgio ; Musio, Antonio ; De Iure, Federico ; Cultrera, Francesco ; Martucci, Antonio ; Iaccarino, Corrado ; Essayed, Walid Ibn ; Ghadirpour, Reza ; Servadei, Franco ; Cavallo, Michele Alessandro ; De Bonis, Pasquale. / Type II odontoid fracture in elderly patients treated conservatively : is fracture healing the goal?. In: European Spine Journal. 2019.
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abstract = "Purpose: Analysis of functional outcome of elderly patients with type II odontoid fractures treated conservatively in relation to their radiological outcome. Methods: A total of 50 geriatric patients with type II odontoid fractures were treated with Aspen/Vista collars. On admission, each patient was assessed assigning ASA score, modified Rankin Scale (mRS-pre) and Charlson Comorbidity Index (CCI). From 12–15 months after treatment, functional evaluations were performed employing a second modified Rankin Scale (mRS-post) together with Neck Disability Index (NDI) and Smiley-Webster pain scale (SWPS). Radiological outcome was evaluated through dynamic cervical spine X-rays at 3 months and cervical spine CT scans 6 months after treatment. Three different conditions were identified: stable union, stable non-union and unstable non-union. Surgery was preferred whenever a fracture gap > 2 mm, an antero-posterior displacement > 5 mm, an odontoid angulation > 11° or neurological deficits occurred. Results: Among the 50 patients, 24 reached a stable union, while 26 a stable non-union. Comparing the two groups, no differences in ASA (p = 0.60), CCI (p = 0.85) and mRS-pre (p = 0.14) were noted. Similarly, no differences in mRS-post (p = 0.96), SWPS (p = 0.85) and NDI (p = 0.51) were observed between patients who reached an osseous fusion and those with a stable fibrous non-union. No effects of age, sex, ASA, mRS-pre, fracture dislocation and radiological outcome were discovered on functional outcome. At logistic regression analysis, female sex and high values of CCI emerged associated with worse NDI. Conclusions: In geriatric type II odontoid fractures, pre-injury clinical status and comorbidities overcome imaging in determining post-treatment level of function. Hard collar immobilization led to a favourable functional outcome with mRS-post, NDI and SWPS values diffusely encouraging whatever a bony union or a fibrous non-union was obtained. Graphical Abstract: These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.].",
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AU - Musio, Antonio

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AU - Cultrera, Francesco

AU - Martucci, Antonio

AU - Iaccarino, Corrado

AU - Essayed, Walid Ibn

AU - Ghadirpour, Reza

AU - Servadei, Franco

AU - Cavallo, Michele Alessandro

AU - De Bonis, Pasquale

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N2 - Purpose: Analysis of functional outcome of elderly patients with type II odontoid fractures treated conservatively in relation to their radiological outcome. Methods: A total of 50 geriatric patients with type II odontoid fractures were treated with Aspen/Vista collars. On admission, each patient was assessed assigning ASA score, modified Rankin Scale (mRS-pre) and Charlson Comorbidity Index (CCI). From 12–15 months after treatment, functional evaluations were performed employing a second modified Rankin Scale (mRS-post) together with Neck Disability Index (NDI) and Smiley-Webster pain scale (SWPS). Radiological outcome was evaluated through dynamic cervical spine X-rays at 3 months and cervical spine CT scans 6 months after treatment. Three different conditions were identified: stable union, stable non-union and unstable non-union. Surgery was preferred whenever a fracture gap > 2 mm, an antero-posterior displacement > 5 mm, an odontoid angulation > 11° or neurological deficits occurred. Results: Among the 50 patients, 24 reached a stable union, while 26 a stable non-union. Comparing the two groups, no differences in ASA (p = 0.60), CCI (p = 0.85) and mRS-pre (p = 0.14) were noted. Similarly, no differences in mRS-post (p = 0.96), SWPS (p = 0.85) and NDI (p = 0.51) were observed between patients who reached an osseous fusion and those with a stable fibrous non-union. No effects of age, sex, ASA, mRS-pre, fracture dislocation and radiological outcome were discovered on functional outcome. At logistic regression analysis, female sex and high values of CCI emerged associated with worse NDI. Conclusions: In geriatric type II odontoid fractures, pre-injury clinical status and comorbidities overcome imaging in determining post-treatment level of function. Hard collar immobilization led to a favourable functional outcome with mRS-post, NDI and SWPS values diffusely encouraging whatever a bony union or a fibrous non-union was obtained. Graphical Abstract: These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.].

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