Abstract
At least four types of endocrine-like cells have been detected histochemically in the mucosa of the human colon and rectum, i.e. argentaffin cells storing 5-hydroxytryptamine (5 HT) and non-argentaffin cells reacting with glucagon, somatostatin and bovine pancreatic peptide (BPP) antibodies. Ultrastructurally, four main types and three rare types of endocrine-like cells have been identified. Among the former cells were: (1) argentaffin EC1 cells, known to store 5 HT and substance P, (2) poorly argyrophil L cells, corresponding to the glucagon-immunoreactive cells storing enteroglucagon or glucagon-like immunoreactivity (GL1), (3) inconstantly argyrophil F-like cells, possibly corresponding to BPP-immunoreactive cells, and (4) fairly argyrophil H cells of unknown function. Rare D cells, corresponding to somatostatin cells, N cells, corresponding to neurotensin cells, and P cells, of unknown function, have been also found.
| Original language | English |
|---|---|
| Pages (from-to) | 227-240 |
| Number of pages | 14 |
| Journal | Cell & Tissue Research |
| Volume | 192 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Sep 1978 |
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Keywords
- Endocrine cells
- Human colon and rectum
- Types
- Ultrastructure, Histochemistry
ASJC Scopus subject areas
- Anatomy
- Clinical Biochemistry
- Cell Biology
Cite this
Types of endocrine cells in the human colon and rectum. / Buffa, R.; Capella, C.; Fontana, P.; Usellini, L.; Solcia, E.
In: Cell & Tissue Research, Vol. 192, No. 2, 09.1978, p. 227-240.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Types of endocrine cells in the human colon and rectum
AU - Buffa, R.
AU - Capella, C.
AU - Fontana, P.
AU - Usellini, L.
AU - Solcia, E.
PY - 1978/9
Y1 - 1978/9
N2 - At least four types of endocrine-like cells have been detected histochemically in the mucosa of the human colon and rectum, i.e. argentaffin cells storing 5-hydroxytryptamine (5 HT) and non-argentaffin cells reacting with glucagon, somatostatin and bovine pancreatic peptide (BPP) antibodies. Ultrastructurally, four main types and three rare types of endocrine-like cells have been identified. Among the former cells were: (1) argentaffin EC1 cells, known to store 5 HT and substance P, (2) poorly argyrophil L cells, corresponding to the glucagon-immunoreactive cells storing enteroglucagon or glucagon-like immunoreactivity (GL1), (3) inconstantly argyrophil F-like cells, possibly corresponding to BPP-immunoreactive cells, and (4) fairly argyrophil H cells of unknown function. Rare D cells, corresponding to somatostatin cells, N cells, corresponding to neurotensin cells, and P cells, of unknown function, have been also found.
AB - At least four types of endocrine-like cells have been detected histochemically in the mucosa of the human colon and rectum, i.e. argentaffin cells storing 5-hydroxytryptamine (5 HT) and non-argentaffin cells reacting with glucagon, somatostatin and bovine pancreatic peptide (BPP) antibodies. Ultrastructurally, four main types and three rare types of endocrine-like cells have been identified. Among the former cells were: (1) argentaffin EC1 cells, known to store 5 HT and substance P, (2) poorly argyrophil L cells, corresponding to the glucagon-immunoreactive cells storing enteroglucagon or glucagon-like immunoreactivity (GL1), (3) inconstantly argyrophil F-like cells, possibly corresponding to BPP-immunoreactive cells, and (4) fairly argyrophil H cells of unknown function. Rare D cells, corresponding to somatostatin cells, N cells, corresponding to neurotensin cells, and P cells, of unknown function, have been also found.
KW - Endocrine cells
KW - Human colon and rectum
KW - Types
KW - Ultrastructure, Histochemistry
UR - http://www.scopus.com/inward/record.url?scp=0018121828&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018121828&partnerID=8YFLogxK
U2 - 10.1007/BF00220741
DO - 10.1007/BF00220741
M3 - Article
C2 - 699014
AN - SCOPUS:0018121828
VL - 192
SP - 227
EP - 240
JO - Cell and Tissue Research
JF - Cell and Tissue Research
SN - 0302-766X
IS - 2
ER -