Abstract
At least four types of endocrine-like cells have been detected histochemically in the mucosa of the human colon and rectum, i.e. argentaffin cells storing 5-hydroxytryptamine (5 HT) and non-argentaffin cells reacting with glucagon, somatostatin and bovine pancreatic peptide (BPP) antibodies. Ultrastructurally, four main types and three rare types of endocrine-like cells have been identified. Among the former cells were: (1) argentaffin EC1 cells, known to store 5 HT and substance P, (2) poorly argyrophil L cells, corresponding to the glucagon-immunoreactive cells storing enteroglucagon or glucagon-like immunoreactivity (GL1), (3) inconstantly argyrophil F-like cells, possibly corresponding to BPP-immunoreactive cells, and (4) fairly argyrophil H cells of unknown function. Rare D cells, corresponding to somatostatin cells, N cells, corresponding to neurotensin cells, and P cells, of unknown function, have been also found.
Original language | English |
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Pages (from-to) | 227-240 |
Number of pages | 14 |
Journal | Cell & Tissue Research |
Volume | 192 |
Issue number | 2 |
DOIs | |
Publication status | Published - Sep 1978 |
Keywords
- Endocrine cells
- Human colon and rectum
- Types
- Ultrastructure, Histochemistry
ASJC Scopus subject areas
- Anatomy
- Clinical Biochemistry
- Cell Biology