Typing with ITS regions of P. carinii from AIDS patients with recurrent pneumonia

P. Margutti, E. Visconti, P. Mencarini, M. Zolfo, S. M E Tamburrini, A. Siracusano, E. Ortona

Research output: Contribution to journalArticlepeer-review

Abstract

To understand the way of reinfection of Pneumocystis carinii we have analyzed the genetic variation at the internal transcribed spacer (ITs) in DNA samples from bronchoalveolar lavage fluid of italian HIV patients who had multiple episodes of P. carinii pneumonia. The presence of the same and/or a new type in both episode suggest the possible occurence of both reactivation of a previously acquired infection and reinfection from an exogenous source. Furthermore the occurence of two different types in the same episode indicate that a mixed infection is common.

Original languageEnglish
JournalJournal of Eukaryotic Microbiology
Volume44
Issue number6
Publication statusPublished - Nov 1997

Keywords

  • Biotyping
  • ITS region
  • P. carinii
  • Reinfection

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Microbiology

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