Ulcerative colitis in remission: Is it possible to predict the risk of relapse?

Silvana Leo, Gioacchino Leandro, Giovanni Di Matteo, Maria Lucia Caruso, Dionigi Lorusso

Research output: Contribution to journalArticlepeer-review


A series of anamnestic, clinical, endoscopic and histologic parameters was evaluated in 64 patients with ulcerative colitis in remission to assess whether any of these had predictive value of relapse. All patients with quiescent disease were followed for at least 6 months. The statistical analysis was carried out by means of likelihood χ2 test, receiver operating characteristic curve, Youden index and stepwise logistic regression. Eighteen patients out of 64 (28 %) had a relapse, in a mean period of 9 months after the beginning of the study. The findings of our study suggest that only three factors were useful in selecting a subpopulation with a higher risk of recurrence: (a) a fiber-poor diet; (b) a number of previous episodes of relapse higher than 10, and (c) the presence of extraintestinal manifestations.

Original languageEnglish
Pages (from-to)217-221
Number of pages5
Issue number4
Publication statusPublished - 1989


  • Extraintestinal manifestations
  • Fiber-poor diet
  • Relapses
  • Remission
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology


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