Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment

Roberta Tittarelli; Simona Pichini; Daniel S. Pedersen; Roberta Pacifici; Monica Moresco; Fabio Pizza; Francesco Paolo Busardò; Giuseppe Plazzi

doi:10.1016/j.forsciint.2017.01.015

Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment

Roberta Tittarelli, Simona Pichini, Daniel S. Pedersen, Roberta Pacifici, Monica Moresco, Fabio Pizza, Francesco Paolo Busardò, Giuseppe Plazzi

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	70-74
Journal	Forensic Science International
Volume	274
DOIs	https://doi.org/10.1016/j.forsciint.2017.01.015
Publication status	Published - 2017

Keywords

Cerebrospinal fluid
GHB
GHB glucuronide
Narcolepsy
Plasma pharmacokinetics
Ultra-high performance liquid chromatography tandem mass spectrometry

Access to Document

10.1016/j.forsciint.2017.01.015

Cite this

Tittarelli, R., Pichini, S., Pedersen, D. S., Pacifici, R., Moresco, M., Pizza, F., Busardò, F. P., & Plazzi, G. (2017). Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment. Forensic Science International, 274, 70-74. https://doi.org/10.1016/j.forsciint.2017.01.015

Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment. / Tittarelli, Roberta; Pichini, Simona; Pedersen, Daniel S.; Pacifici, Roberta; Moresco, Monica; Pizza, Fabio; Busardò, Francesco Paolo; Plazzi, Giuseppe.

In: Forensic Science International, Vol. 274, 2017, p. 70-74.

Research output: Contribution to journal › Article › peer-review

Tittarelli, R, Pichini, S, Pedersen, DS, Pacifici, R, Moresco, M, Pizza, F, Busardò, FP & Plazzi, G 2017, 'Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment', Forensic Science International, vol. 274, pp. 70-74. https://doi.org/10.1016/j.forsciint.2017.01.015

Tittarelli, Roberta ; Pichini, Simona ; Pedersen, Daniel S. ; Pacifici, Roberta ; Moresco, Monica ; Pizza, Fabio ; Busardò, Francesco Paolo ; Plazzi, Giuseppe. / Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment. In: Forensic Science International. 2017 ; Vol. 274. pp. 70-74.

@article{b57cbde0aaa240969a8135ebc27b3598,

title = "Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment",

keywords = "Cerebrospinal fluid, GHB, GHB glucuronide, Narcolepsy, Plasma pharmacokinetics, Ultra-high performance liquid chromatography tandem mass spectrometry",

author = "Roberta Tittarelli and Simona Pichini and Pedersen, {Daniel S.} and Roberta Pacifici and Monica Moresco and Fabio Pizza and Busard{\`o}, {Francesco Paolo} and Giuseppe Plazzi",

note = "Ricercatore distaccato presso IRCCS a seguito Convenzione esclusiva con Universit{\`a} di Bologna (Pizza Fabio, Plazzi Giuseppe) ",

year = "2017",

doi = "10.1016/j.forsciint.2017.01.015",

language = "English",

volume = "274",

pages = "70--74",

journal = "Forensic Science International",

issn = "0379-0738",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment

AU - Tittarelli, Roberta

AU - Pichini, Simona

AU - Pedersen, Daniel S.

AU - Pacifici, Roberta

AU - Moresco, Monica

AU - Pizza, Fabio

AU - Busardò, Francesco Paolo

AU - Plazzi, Giuseppe

N1 - Ricercatore distaccato presso IRCCS a seguito Convenzione esclusiva con Università di Bologna (Pizza Fabio, Plazzi Giuseppe)

PY - 2017

Y1 - 2017

KW - Cerebrospinal fluid

KW - GHB

KW - GHB glucuronide

KW - Narcolepsy

KW - Plasma pharmacokinetics

KW - Ultra-high performance liquid chromatography tandem mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=85010900168&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85010900168&partnerID=8YFLogxK

U2 - 10.1016/j.forsciint.2017.01.015

DO - 10.1016/j.forsciint.2017.01.015

M3 - Article

C2 - 28139340

AN - SCOPUS:85010900168

VL - 274

SP - 70

EP - 74

JO - Forensic Science International

JF - Forensic Science International

SN - 0379-0738

ER -

Ultra-high-performance liquid chromatography tandem mass spectrometry determination of GHB, GHB-glucuronide in plasma and cerebrospinal fluid of narcoleptic patients under sodium oxybate treatment

Keywords

Access to Document

Other files and links

Cite this