Ultrafiltration processes in blood treatment

Gabriele Iorio, Enrico Drioli, Bruno Memoli, Vittorio E. Andreucci, Marco Salvatore, Bruno Alfano

Research output: Contribution to journalArticlepeer-review


The major drawback of hemofiltration is the observed reduction of the permeate flux, as compared to what was expected, due to the occurrence of concentration polarization phenomena. This effect is also related to a change in the overall filter selectivity and performance, in particular as far as intermediate molecular weight species are concerned. In the present paper an experimental analysis has been carried out on some commercial hemofilters, adopted both in vivo and in vitro. A scintigraphic technique has been employed for the ultrafiltration tests on plasma solution in order to better visualize the interfacial phenomena on the membrane. A theoretical simulation of the system behavior has been attempted, with the formulation of a mathematical model able to predict the protein concentration distribution within the filter.

Original languageEnglish
Pages (from-to)297-311
Number of pages15
JournalJournal of Membrane Science
Issue numberC
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Filtration and Separation
  • Polymers and Plastics


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