Ultrasonic evaluation of gallbladder emptying with ceruletide

M. Muraca, V. Cianci, M. T. Vilei, D. Burighel

Research output: Contribution to journalArticlepeer-review


In order to develop a practical and reproducible method to assess gallbladder function, gallbladder emptying was studied by ultrasound in 27 gallstone patients after i.m. administration of ceruletide (0.3 μg/kg), and the procedure was compared to oral cholecystography with fatty meal. Maximal percent gallbladder contraction was reached in all patients 30 min after ceruletide. Maximal percent contractions were 47.5 ± 27.7 during ultrasound with ceruletide and 33.9 ± 16.3 during oral cholecystography with fatty meal (p = 0.03). A significant linear relationship was found between the results obtained with the two different procedures (r = 0.57; p = 0.002). Serial ultrasound determinations of gallbladder emptying were performed in 16 patients. Day-to-day variation was below 20% in 11 subjects, and it ranged between 20 and 40% in 5 subjects. Minor side effects were observed in 9 patients. Ultrasound determination of gallbladder emptying after ceruletide appears to be a practical and reliable method to assess gallbladder function.

Original languageEnglish
Pages (from-to)38-39
Number of pages2
JournalItalian Journal of Gastroenterology
Issue number1
Publication statusPublished - 1996


  • Gallbladder emptying
  • Oral cholecystography
  • Ultrasonography

ASJC Scopus subject areas

  • Gastroenterology


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