Ultrasonic evaluation of gallbladder emptying with ceruletide

comparison to oral cholecystography with fatty meal

M. Muraca, V. Cianci, L. Miconi, M. T. Vilei

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Assessment of gallbladder function is required prior to nonsurgical treatment of gallstones. In order to develop a practical and reproducible method of evaluation, gallbladder emptying was studied by ultrasound (US) in 55 gallstone patients after intramuscular administration of ceruletide (0.3 μg/kg). In 27 of these subjects, the US procedure was compared to oral cholecystography (OCG) with fatty meal. Maximal percent gallbladder contraction was reached 30 min after ceruletide in all patients. Maximal percent contractions were 47.5±27.7 during US with ceruletide and 33.9±16.3 during OCG with fatty meal (p = 0.03). A significant linear relationship was found between the results obtained with the two different procedures (r=0.57; p = 0.002). Serial US determinations of gallbladder emptying were performed in 16 patients. Individual variation was below 20% in 11 subjects, and in five subjects it ranged between 20 and 40%. Minor, self-limiting side effects were observed in 13 patients. US determination of gallbladder emptying after ceruletide appears to be a practical and reliable method to assess gallbladder function.

Original languageEnglish
Pages (from-to)235-238
Number of pages4
JournalAbdominal Imaging
Volume19
Issue number3
DOIs
Publication statusPublished - May 1994

Fingerprint

Gallbladder Emptying
Cholecystography
Ceruletide
Ultrasonics
Meals
Gallbladder
Gallstones

Keywords

  • Abdomen, US diagnosis
  • Gallbladder, effect of ceruletide
  • Oral cholecystography, with fatty meal

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Urology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Ultrasonic evaluation of gallbladder emptying with ceruletide : comparison to oral cholecystography with fatty meal. / Muraca, M.; Cianci, V.; Miconi, L.; Vilei, M. T.

In: Abdominal Imaging, Vol. 19, No. 3, 05.1994, p. 235-238.

Research output: Contribution to journalArticle

Muraca, M. ; Cianci, V. ; Miconi, L. ; Vilei, M. T. / Ultrasonic evaluation of gallbladder emptying with ceruletide : comparison to oral cholecystography with fatty meal. In: Abdominal Imaging. 1994 ; Vol. 19, No. 3. pp. 235-238.
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