Abstract
Assessment of gallbladder function is required prior to nonsurgical treatment of gallstones. In order to develop a practical and reproducible method of evaluation, gallbladder emptying was studied by ultrasound (US) in 55 gallstone patients after intramuscular administration of ceruletide (0.3 μg/kg). In 27 of these subjects, the US procedure was compared to oral cholecystography (OCG) with fatty meal. Maximal percent gallbladder contraction was reached 30 min after ceruletide in all patients. Maximal percent contractions were 47.5±27.7 during US with ceruletide and 33.9±16.3 during OCG with fatty meal (p = 0.03). A significant linear relationship was found between the results obtained with the two different procedures (r=0.57; p = 0.002). Serial US determinations of gallbladder emptying were performed in 16 patients. Individual variation was below 20% in 11 subjects, and in five subjects it ranged between 20 and 40%. Minor, self-limiting side effects were observed in 13 patients. US determination of gallbladder emptying after ceruletide appears to be a practical and reliable method to assess gallbladder function.
| Original language | English |
|---|---|
| Pages (from-to) | 235-238 |
| Number of pages | 4 |
| Journal | Abdominal Imaging |
| Volume | 19 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1994 |
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Keywords
- Abdomen, US diagnosis
- Gallbladder, effect of ceruletide
- Oral cholecystography, with fatty meal
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Urology
- Radiology Nuclear Medicine and imaging
- Gastroenterology
Cite this
Ultrasonic evaluation of gallbladder emptying with ceruletide : comparison to oral cholecystography with fatty meal. / Muraca, M.; Cianci, V.; Miconi, L.; Vilei, M. T.
In: Abdominal Imaging, Vol. 19, No. 3, 05.1994, p. 235-238.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ultrasonic evaluation of gallbladder emptying with ceruletide
T2 - comparison to oral cholecystography with fatty meal
AU - Muraca, M.
AU - Cianci, V.
AU - Miconi, L.
AU - Vilei, M. T.
PY - 1994/5
Y1 - 1994/5
N2 - Assessment of gallbladder function is required prior to nonsurgical treatment of gallstones. In order to develop a practical and reproducible method of evaluation, gallbladder emptying was studied by ultrasound (US) in 55 gallstone patients after intramuscular administration of ceruletide (0.3 μg/kg). In 27 of these subjects, the US procedure was compared to oral cholecystography (OCG) with fatty meal. Maximal percent gallbladder contraction was reached 30 min after ceruletide in all patients. Maximal percent contractions were 47.5±27.7 during US with ceruletide and 33.9±16.3 during OCG with fatty meal (p = 0.03). A significant linear relationship was found between the results obtained with the two different procedures (r=0.57; p = 0.002). Serial US determinations of gallbladder emptying were performed in 16 patients. Individual variation was below 20% in 11 subjects, and in five subjects it ranged between 20 and 40%. Minor, self-limiting side effects were observed in 13 patients. US determination of gallbladder emptying after ceruletide appears to be a practical and reliable method to assess gallbladder function.
AB - Assessment of gallbladder function is required prior to nonsurgical treatment of gallstones. In order to develop a practical and reproducible method of evaluation, gallbladder emptying was studied by ultrasound (US) in 55 gallstone patients after intramuscular administration of ceruletide (0.3 μg/kg). In 27 of these subjects, the US procedure was compared to oral cholecystography (OCG) with fatty meal. Maximal percent gallbladder contraction was reached 30 min after ceruletide in all patients. Maximal percent contractions were 47.5±27.7 during US with ceruletide and 33.9±16.3 during OCG with fatty meal (p = 0.03). A significant linear relationship was found between the results obtained with the two different procedures (r=0.57; p = 0.002). Serial US determinations of gallbladder emptying were performed in 16 patients. Individual variation was below 20% in 11 subjects, and in five subjects it ranged between 20 and 40%. Minor, self-limiting side effects were observed in 13 patients. US determination of gallbladder emptying after ceruletide appears to be a practical and reliable method to assess gallbladder function.
KW - Abdomen, US diagnosis
KW - Gallbladder, effect of ceruletide
KW - Oral cholecystography, with fatty meal
UR - http://www.scopus.com/inward/record.url?scp=0028280468&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028280468&partnerID=8YFLogxK
U2 - 10.1007/BF00203515
DO - 10.1007/BF00203515
M3 - Article
VL - 19
SP - 235
EP - 238
JO - Abdominal Imaging
JF - Abdominal Imaging
SN - 0942-8925
IS - 3
ER -