Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: Power Doppler signal predicts short-term relapse

Carlo A. Sciré; Carlomaurizio Montecucco; Veronica Codullo; Oscar Epis; Monica Todoerti; Roberto Caporali

doi:10.1093/rheumatology/kep171

Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: Power Doppler signal predicts short-term relapse

Carlo A. Sciré, Carlomaurizio Montecucco, Veronica Codullo, Oscar Epis, Monica Todoerti, Roberto Caporali

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: This study aimed to evaluate the usefulness of a systematic musculoskeletal ultrasonographic (US) assessment in the detection of residual disease activity in patients with early RA who achieved clinical remission. Methods: We prospectively studied 106 early RA patients receiving conventional DMARDs according to a disease activity score (DAS)-steered therapeutic protocol over a 24-month period. Standard evaluation included clinical, laboratory, functional and systematic (44 joints) US assessment. US indexes of grey scale (GS) and power Doppler (PD) synovitis were correlated with clinical evaluation, laboratory indexes and clinical outcome. Clinical remission was defined when DAS was

Original language	English
Pages (from-to)	1092-1097
Number of pages	6
Journal	Rheumatology
Volume	48
Issue number	9
DOIs	https://doi.org/10.1093/rheumatology/kep171
Publication status	Published - Sep 2009

Keywords

Arthritis
Disease activity
Doppler
Early diagnosis
Prognosis
Remission
Rheumatoid
Treatment outcome
Ultrasonography

ASJC Scopus subject areas

Rheumatology
Pharmacology (medical)
Medicine(all)

Access to Document

10.1093/rheumatology/kep171

Cite this

@article{a77f1c3d468f4a63a23506f6d097689b,

title = "Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: Power Doppler signal predicts short-term relapse",

abstract = "Objective: This study aimed to evaluate the usefulness of a systematic musculoskeletal ultrasonographic (US) assessment in the detection of residual disease activity in patients with early RA who achieved clinical remission. Methods: We prospectively studied 106 early RA patients receiving conventional DMARDs according to a disease activity score (DAS)-steered therapeutic protocol over a 24-month period. Standard evaluation included clinical, laboratory, functional and systematic (44 joints) US assessment. US indexes of grey scale (GS) and power Doppler (PD) synovitis were correlated with clinical evaluation, laboratory indexes and clinical outcome. Clinical remission was defined when DAS was ",

keywords = "Arthritis, Disease activity, Doppler, Early diagnosis, Prognosis, Remission, Rheumatoid, Treatment outcome, Ultrasonography",

author = "Scir{\'e}, {Carlo A.} and Carlomaurizio Montecucco and Veronica Codullo and Oscar Epis and Monica Todoerti and Roberto Caporali",

year = "2009",

month = sep,

doi = "10.1093/rheumatology/kep171",

language = "English",

volume = "48",

pages = "1092--1097",

journal = "Rheumatology",

issn = "1462-0324",

publisher = ". Published by Oxford University Press on behalf of the British Society for Rheumatology",

number = "9",

}

TY - JOUR

T1 - Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission

T2 - Power Doppler signal predicts short-term relapse

AU - Sciré, Carlo A.

AU - Montecucco, Carlomaurizio

AU - Codullo, Veronica

AU - Epis, Oscar

AU - Todoerti, Monica

AU - Caporali, Roberto

PY - 2009/9

Y1 - 2009/9

N2 - Objective: This study aimed to evaluate the usefulness of a systematic musculoskeletal ultrasonographic (US) assessment in the detection of residual disease activity in patients with early RA who achieved clinical remission. Methods: We prospectively studied 106 early RA patients receiving conventional DMARDs according to a disease activity score (DAS)-steered therapeutic protocol over a 24-month period. Standard evaluation included clinical, laboratory, functional and systematic (44 joints) US assessment. US indexes of grey scale (GS) and power Doppler (PD) synovitis were correlated with clinical evaluation, laboratory indexes and clinical outcome. Clinical remission was defined when DAS was

AB - Objective: This study aimed to evaluate the usefulness of a systematic musculoskeletal ultrasonographic (US) assessment in the detection of residual disease activity in patients with early RA who achieved clinical remission. Methods: We prospectively studied 106 early RA patients receiving conventional DMARDs according to a disease activity score (DAS)-steered therapeutic protocol over a 24-month period. Standard evaluation included clinical, laboratory, functional and systematic (44 joints) US assessment. US indexes of grey scale (GS) and power Doppler (PD) synovitis were correlated with clinical evaluation, laboratory indexes and clinical outcome. Clinical remission was defined when DAS was

KW - Arthritis

KW - Disease activity

KW - Doppler

KW - Early diagnosis

KW - Prognosis

KW - Remission

KW - Rheumatoid

KW - Treatment outcome

KW - Ultrasonography

UR - http://www.scopus.com/inward/record.url?scp=70349784010&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70349784010&partnerID=8YFLogxK

U2 - 10.1093/rheumatology/kep171

DO - 10.1093/rheumatology/kep171

M3 - Article

C2 - 19561156

AN - SCOPUS:70349784010

VL - 48

SP - 1092

EP - 1097

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 9

ER -

Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: Power Doppler signal predicts short-term relapse

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this