Ultrasound assessment of sural nerve in Charcot-Marie-Tooth 1A neuropathy

C. Pazzaglia; I. Minciotti; D. Coraci; C. Briani; L. Padua

doi:10.1016/j.clinph.2013.02.020

Ultrasound assessment of sural nerve in Charcot-Marie-Tooth 1A neuropathy

C. Pazzaglia, I. Minciotti, D. Coraci, C. Briani, L. Padua

Fondazione Don Carlo Gnocchi Onlus

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p

Original language	English
Pages (from-to)	1695-1699
Number of pages	5
Journal	Clinical Neurophysiology
Volume	124
Issue number	8
DOIs	https://doi.org/10.1016/j.clinph.2013.02.020
Publication status	Published - Aug 2013

Keywords

Charcot-Marie-Tooth
Sural nerve
Ultrasound assessment

ASJC Scopus subject areas

Clinical Neurology
Neurology
Physiology (medical)
Sensory Systems

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title = "Ultrasound assessment of sural nerve in Charcot-Marie-Tooth 1A neuropathy",

abstract = "Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p",

keywords = "Charcot-Marie-Tooth, Sural nerve, Ultrasound assessment",

author = "C. Pazzaglia and I. Minciotti and D. Coraci and C. Briani and L. Padua",

year = "2013",

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AU - Pazzaglia, C.

AU - Minciotti, I.

AU - Coraci, D.

AU - Briani, C.

AU - Padua, L.

PY - 2013/8

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N2 - Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p

AB - Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p

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