Abstract
Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p
| Original language | English |
|---|---|
| Pages (from-to) | 1695-1699 |
| Number of pages | 5 |
| Journal | Clinical Neurophysiology |
| Volume | 124 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2013 |
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Keywords
- Charcot-Marie-Tooth
- Sural nerve
- Ultrasound assessment
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Physiology (medical)
- Sensory Systems
Cite this
Ultrasound assessment of sural nerve in Charcot-Marie-Tooth 1A neuropathy. / Pazzaglia, C.; Minciotti, I.; Coraci, D.; Briani, C.; Padua, L.
In: Clinical Neurophysiology, Vol. 124, No. 8, 08.2013, p. 1695-1699.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ultrasound assessment of sural nerve in Charcot-Marie-Tooth 1A neuropathy
AU - Pazzaglia, C.
AU - Minciotti, I.
AU - Coraci, D.
AU - Briani, C.
AU - Padua, L.
PY - 2013/8
Y1 - 2013/8
N2 - Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p
AB - Objective: Nerve ultrasound (US) has been used to study peripheral nerve disease, and increase of the cross-sectional area (CSA) has been described in demyelinating polyneuropathy. The objective of the current study is to characterise the US features of the sural nerve in a sample of Charcot-Marie-Tooth (CMT) 1A patients. Methods: A total of 20 CMT1A patients were enrolled. As control group we studied 37 age- and sex-matched subjects. All patients underwent clinical examination, neurophysiology and US evaluation of the bilateral sural nerve and right ulnar nerve. US results were correlated with neurophysiology and clinical data. Results: Sural nerve CSA was not increased in the majority of patients (70%), whereas an increased ulnar nerve CSA was present in the whole sample. Inverse relations were found between CSA of the ulnar nerve and body mass index (BMI) (. p
KW - Charcot-Marie-Tooth
KW - Sural nerve
KW - Ultrasound assessment
UR - http://www.scopus.com/inward/record.url?scp=84880160110&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880160110&partnerID=8YFLogxK
U2 - 10.1016/j.clinph.2013.02.020
DO - 10.1016/j.clinph.2013.02.020
M3 - Article
C2 - 23669651
AN - SCOPUS:84880160110
VL - 124
SP - 1695
EP - 1699
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
SN - 1388-2457
IS - 8
ER -