Ultrasound imaging for the rheumatologist XXVIII. Impact of sonographic knee joint involvement in recent-onset inflammatory polyarthritis

Carlo Alberto Scirè, Annamaria Iagnocco, Gary Meenagh, Lucrezia Riente, Emilio Filippucci, Andrea Delle Sedie, Veronica Codullo, Walter Grassi, Stefano Bombardieri, Guido Valesini, Carlomaurizio Montecucco

Research output: Contribution to journalArticle


Objective: To assess the impact of the knee joint inflammation, detected by ultrasonography (US), on functional disability in patients with recent-onset inflammatory polyarthritis (IP). Methods: We included patients who had IP for less than 12 months and who had more than 5 swollen joints. All patients were assessed clinically at baseline. US was used to identify joint inflammation at multiple joint sites including: hands, wrists, elbows, shoulders, knees, ankles and feet. Joint group involvement was defined when at least one joint showed intra-articular signs of inflammation (synovial fluid abnormalities and/or synovial hypertrophy), according to the OMERACT definitions. Functional disability was measured using the health assessment questionnaire (HAQ) score. All patients with complete clinical and US data were included in the analysis. Results: Patients with US knee involvement showed more active and severe disease at baseline. The mean difference of HAQ between patients with and without US knee inflammation was 0.42 (95%CI 0.22, 0.62; p

Original languageEnglish
Pages (from-to)449-453
Number of pages5
JournalClinical and Experimental Rheumatology
Issue number4
Publication statusPublished - 2010



  • Arthritis
  • Functional disability
  • Knee joint
  • Ultrasonography

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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