Ultrasound point shear wave elastography assessment of liver and spleen stiffness: Effect of training on repeatability of measurements

Research output: Contribution to journalArticle

Abstract

Objectives: To evaluate reproducibility of measurements of spleen stiffness (SS) and liver stiffness (LS) at several sites by using point shear wave elastography (pSWE) and to investigate any training effect. Methods: Healthy volunteers were consecutively enrolled. Measurements of SS and LS were performed by an expert (observer 1) and a novice (observer 2) at three different sites of liver and spleen. To assess the effect of training the study was conducted in two periods (period 1 and period 2). Concordance correlation coefficient was used to assess intra-observer and inter-observer reproducibility. Results: A total of 92 subjects (67 men and 25 women) were enrolled in the study. Both intra-observer and inter-observer agreement were higher for the liver than for the spleen. Overall, the highest intra-observer and inter-observer agreement were obtained for the assessment of LS through intercostal space, and for measurements at this site there was a significantly better performance of observer 2 after the training period. For both observers, training improved the repeatability of SS measurements at all sites. A good intra-observer agreement was obtained only for measurements at the spleen lower pole. Conclusions: The results of this study show that a learning curve in pSWE acquisition should be taken into account both for SS and LS measurements. Key Points: • Reproducibility of SS measurements depends on the expertise of the operator. • To achieve good reproducibility between measurements a training period is required. • A learning curve in pSWE acquisition should be taken into account. • SS measurements are less reproducible than LS measurements.

Original languageEnglish
Pages (from-to)1283-1289
Number of pages7
JournalEuropean Radiology
Volume24
Issue number6
DOIs
Publication statusPublished - 2014

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Elasticity Imaging Techniques
Spleen
Liver
Learning Curve
Healthy Volunteers

Keywords

  • Concordance correlation coefficient
  • Liver
  • Reproducibility studies
  • Shearwave elastography
  • Spleen
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Ultrasound point shear wave elastography assessment of liver and spleen stiffness: Effect of training on repeatability of measurements",
abstract = "Objectives: To evaluate reproducibility of measurements of spleen stiffness (SS) and liver stiffness (LS) at several sites by using point shear wave elastography (pSWE) and to investigate any training effect. Methods: Healthy volunteers were consecutively enrolled. Measurements of SS and LS were performed by an expert (observer 1) and a novice (observer 2) at three different sites of liver and spleen. To assess the effect of training the study was conducted in two periods (period 1 and period 2). Concordance correlation coefficient was used to assess intra-observer and inter-observer reproducibility. Results: A total of 92 subjects (67 men and 25 women) were enrolled in the study. Both intra-observer and inter-observer agreement were higher for the liver than for the spleen. Overall, the highest intra-observer and inter-observer agreement were obtained for the assessment of LS through intercostal space, and for measurements at this site there was a significantly better performance of observer 2 after the training period. For both observers, training improved the repeatability of SS measurements at all sites. A good intra-observer agreement was obtained only for measurements at the spleen lower pole. Conclusions: The results of this study show that a learning curve in pSWE acquisition should be taken into account both for SS and LS measurements. Key Points: • Reproducibility of SS measurements depends on the expertise of the operator. • To achieve good reproducibility between measurements a training period is required. • A learning curve in pSWE acquisition should be taken into account. • SS measurements are less reproducible than LS measurements.",
keywords = "Concordance correlation coefficient, Liver, Reproducibility studies, Shearwave elastography, Spleen, Ultrasound",
author = "Giovanna Ferraioli and Carmine Tinelli and Raffaella Lissandrin and Mabel Zicchetti and Stefano Bernuzzi and Laura Salvaneschi and Carlo Filice",
year = "2014",
doi = "10.1007/s00330-014-3140-y",
language = "English",
volume = "24",
pages = "1283--1289",
journal = "European Radiology",
issn = "0938-7994",
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number = "6",

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T1 - Ultrasound point shear wave elastography assessment of liver and spleen stiffness

T2 - Effect of training on repeatability of measurements

AU - Ferraioli, Giovanna

AU - Tinelli, Carmine

AU - Lissandrin, Raffaella

AU - Zicchetti, Mabel

AU - Bernuzzi, Stefano

AU - Salvaneschi, Laura

AU - Filice, Carlo

PY - 2014

Y1 - 2014

N2 - Objectives: To evaluate reproducibility of measurements of spleen stiffness (SS) and liver stiffness (LS) at several sites by using point shear wave elastography (pSWE) and to investigate any training effect. Methods: Healthy volunteers were consecutively enrolled. Measurements of SS and LS were performed by an expert (observer 1) and a novice (observer 2) at three different sites of liver and spleen. To assess the effect of training the study was conducted in two periods (period 1 and period 2). Concordance correlation coefficient was used to assess intra-observer and inter-observer reproducibility. Results: A total of 92 subjects (67 men and 25 women) were enrolled in the study. Both intra-observer and inter-observer agreement were higher for the liver than for the spleen. Overall, the highest intra-observer and inter-observer agreement were obtained for the assessment of LS through intercostal space, and for measurements at this site there was a significantly better performance of observer 2 after the training period. For both observers, training improved the repeatability of SS measurements at all sites. A good intra-observer agreement was obtained only for measurements at the spleen lower pole. Conclusions: The results of this study show that a learning curve in pSWE acquisition should be taken into account both for SS and LS measurements. Key Points: • Reproducibility of SS measurements depends on the expertise of the operator. • To achieve good reproducibility between measurements a training period is required. • A learning curve in pSWE acquisition should be taken into account. • SS measurements are less reproducible than LS measurements.

AB - Objectives: To evaluate reproducibility of measurements of spleen stiffness (SS) and liver stiffness (LS) at several sites by using point shear wave elastography (pSWE) and to investigate any training effect. Methods: Healthy volunteers were consecutively enrolled. Measurements of SS and LS were performed by an expert (observer 1) and a novice (observer 2) at three different sites of liver and spleen. To assess the effect of training the study was conducted in two periods (period 1 and period 2). Concordance correlation coefficient was used to assess intra-observer and inter-observer reproducibility. Results: A total of 92 subjects (67 men and 25 women) were enrolled in the study. Both intra-observer and inter-observer agreement were higher for the liver than for the spleen. Overall, the highest intra-observer and inter-observer agreement were obtained for the assessment of LS through intercostal space, and for measurements at this site there was a significantly better performance of observer 2 after the training period. For both observers, training improved the repeatability of SS measurements at all sites. A good intra-observer agreement was obtained only for measurements at the spleen lower pole. Conclusions: The results of this study show that a learning curve in pSWE acquisition should be taken into account both for SS and LS measurements. Key Points: • Reproducibility of SS measurements depends on the expertise of the operator. • To achieve good reproducibility between measurements a training period is required. • A learning curve in pSWE acquisition should be taken into account. • SS measurements are less reproducible than LS measurements.

KW - Concordance correlation coefficient

KW - Liver

KW - Reproducibility studies

KW - Shearwave elastography

KW - Spleen

KW - Ultrasound

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