TY - JOUR
T1 - Ultrasound stimulus to enhance the bone regeneration capability of gelatin cryogels.
AU - Fassina, Lorenzo
AU - Visai, Livia
AU - Magenes, Giovanni
AU - Schelfhout, Jorg
AU - Bloise, Nora
AU - Riva, Federica
AU - Omes, Claudia
AU - Avanzini, Maria Antonietta
AU - Cusella De Angelis, Maria Gabriella
AU - Benazzo, Francesco
AU - Dierick, Manuel
AU - Van Hoorebeke, Luc
AU - Dubruel, Peter
AU - Van Vlierberghe, Sandra
PY - 2013
Y1 - 2013
N2 - In the present study, gelatin-based cryogels have been seeded with human SAOS-2 osteoblasts. In order to overcome the drawbacks associated with in vitro culture systems, such as limited diffusion and inhomogeneous cell-matrix distribution, this work describes the application of ultrasounds (average power, 149 mW; frequency, 1.5 MHz) to physically enhance the cell culture in vitro. The results indicate that the physical stimulation of cell-seeded gelatin-based cryogels upregulates the bone matrix production.
AB - In the present study, gelatin-based cryogels have been seeded with human SAOS-2 osteoblasts. In order to overcome the drawbacks associated with in vitro culture systems, such as limited diffusion and inhomogeneous cell-matrix distribution, this work describes the application of ultrasounds (average power, 149 mW; frequency, 1.5 MHz) to physically enhance the cell culture in vitro. The results indicate that the physical stimulation of cell-seeded gelatin-based cryogels upregulates the bone matrix production.
UR - http://www.scopus.com/inward/record.url?scp=84902612959&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902612959&partnerID=8YFLogxK
M3 - Article
C2 - 24109820
VL - 2013
SP - 846
EP - 849
JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
SN - 1557-170X
ER -