Ultrasound stimulus to enhance the bone regeneration capability of gelatin cryogels

Lorenzo Fassina, Livia Visai, Giovanni Magenes, Jorg Schelfhout, Nora Bloise, Federica Riva, Claudia Omes, Maria Antonietta Avanzini, Maria Gabriella Cusella De Angelis, Francesco Benazzo, Manuel Dierick, Luc Van Hoorebeke, Peter Dubruel, Sandra Van Vlierberghe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In the present study, gelatin-based cryogels have been seeded with human SAOS-2 osteoblasts. In order to overcome the drawbacks associated with in vitro culture systems, such as limited diffusion and inhomogeneous cell-matrix distribution, this work describes the application of ultrasounds (average power, 149 mW; frequency, 1.5 MHz) to physically enhance the cell culture in vitro. The results indicate that the physical stimulation of cell-seeded gelatin-based cryogels upregulates the bone matrix production.

Original languageEnglish
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages846-849
Number of pages4
DOIs
Publication statusPublished - 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: Jul 3 2013Jul 7 2013

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period7/3/137/7/13

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Fingerprint Dive into the research topics of 'Ultrasound stimulus to enhance the bone regeneration capability of gelatin cryogels'. Together they form a unique fingerprint.

  • Cite this

    Fassina, L., Visai, L., Magenes, G., Schelfhout, J., Bloise, N., Riva, F., Omes, C., Avanzini, M. A., Cusella De Angelis, M. G., Benazzo, F., Dierick, M., Van Hoorebeke, L., Dubruel, P., & Van Vlierberghe, S. (2013). Ultrasound stimulus to enhance the bone regeneration capability of gelatin cryogels. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 846-849). [6609633] https://doi.org/10.1109/EMBC.2013.6609633