Besides 5-hydroxytryptamine-storing EC cells, four types of endocrine non-EC cells have been identified in the dog intestinal mucosa: the S and D cells, mainly concentrated in the upper tracts of the small intestine, the L cell, concentrated in the lower tracts, and the I cell showing intermediate patterns between S and L cells. In immunofluorescence tests epithelial endocrine-like cells reacting to antisecretin sera were found in the duodenal mucosa. Only the S cell seems to exactly reproduce the distribution of secretin activity in different portions of gastrointestinal mucosa.
ASJC Scopus subject areas
- Cell Biology