Ultrastructural alterations of atrophic skin lesions due to several applications of topical corticosteroid, under occlusive bandage, are noticed in a patient suffering from psoriasis. It is particularly underlined how the protracted action of the corticosteroid may induce epidermal alterations (the keratinosomes appear optically empty), modifications of the dermoepidermal junction and of the dermis (polystratification of the basal lamina, degeneration of the elastic fibers, a decrease of fibroblasts activity). It is supposed that all these alterations may be due to some modifications of the mucopolysaccharidic complex induced by the corticosteroid.
|Translated title of the contribution||Ultrastructural changes in skin rendered atrophic due to application of a topical corticosteroid in a psoriasis patient|
|Title of host publication||G.ITAL.DERM.MINERVA DERM.|
|Number of pages||7|
|Publication status||Published - 1974|
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