Ultrastructural evolution of experimentally induced lipid inclusions in rat and mouse hepatocytes indicative for the recovery of livers from effects of benzidamine and triacetyloleandomycin

E. Garaci, W. Djaczenko

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Both benzidamine (BA) and triacetyloleandomycin (TAO) provoke liver steatosis. Lipid inclusions were in spatial contact with mitochondria. Whorls of electron opaque membranes developed in lipid inclusions in later experimental periods with signs of recovery of the liver. It is concluded that the content of lipid inclusions may be used in repair processes and that the formation of whorls of membranes might be an indication that drug produced ultrastructural modifications of hepatocytes are reversible.

Original languageEnglish
Title of host publicationAnnali Sclavo - Rivista di Microbiologia e di Immunologia
Pages18-28
Number of pages11
Volume16
Edition1
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Medicine(all)

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