Both benzidamine (BA) and triacetyloleandomycin (TAO) provoke liver steatosis. Lipid inclusions were in spatial contact with mitochondria. Whorls of electron opaque membranes developed in lipid inclusions in later experimental periods with signs of recovery of the liver. It is concluded that the content of lipid inclusions may be used in repair processes and that the formation of whorls of membranes might be an indication that drug produced ultrastructural modifications of hepatocytes are reversible.
|Title of host publication||Annali Sclavo - Rivista di Microbiologia e di Immunologia|
|Number of pages||11|
|Publication status||Published - 1974|
ASJC Scopus subject areas