Abstract
Tissue samples from 19 HIV-seropositive immunocompromised patients suffering from oral hairy leukoplakia, chronic vesicular or ulcerative herpes simplex, chronic nonmetameric herpes zoster, secondary syphilis, condylomata acuminata, molluscum contagiosum, or disseminated cutaneous mycobacteriosis were examined ultrastructurally in order to better define the fine structure of the causative organisms in parasitic conditions and to clarify the host- parasite relationships. Taking into account the few data in the literature regarding the same disorders in immunocompetent subjects, no striking differences in the morphology of the infectious agents or in the types of parasitism were found. Nevertheless, isolated herpesvirus and papillomavirus virions were found outside the infected cells, and this observation, if confirmed in a larger series of cases, could suggest a persistent infectivity of the lesions in immunocompromised patients. Moreover, electron microscopy proved to be useful for diagnostic purposes; in one case of disseminated cutaneous mycobacteriosis, repeated cultures failed to grow the organism.
| Original language | English |
|---|---|
| Pages (from-to) | 320-325 |
| Number of pages | 6 |
| Journal | American Journal of Dermatopathology |
| Volume | 15 |
| Issue number | 4 |
| Publication status | Published - 1993 |
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Keywords
- AIDS
- Chronic herpes simplex
- Chronic herpes zoster
- Condylomata acuminata
- Cutaneous mycobacteriosis
- Molluscum contagiosum
- Oral hairy leukoplakia
- Secondary syphilis
ASJC Scopus subject areas
- Dermatology
- Pathology and Forensic Medicine
Cite this
Ultrastructural findings in mucocutaneous infections of patients seropositive to HIV. / Cavicchini, S.; Brezzi, A.; Alessi, E.
In: American Journal of Dermatopathology, Vol. 15, No. 4, 1993, p. 320-325.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ultrastructural findings in mucocutaneous infections of patients seropositive to HIV
AU - Cavicchini, S.
AU - Brezzi, A.
AU - Alessi, E.
PY - 1993
Y1 - 1993
N2 - Tissue samples from 19 HIV-seropositive immunocompromised patients suffering from oral hairy leukoplakia, chronic vesicular or ulcerative herpes simplex, chronic nonmetameric herpes zoster, secondary syphilis, condylomata acuminata, molluscum contagiosum, or disseminated cutaneous mycobacteriosis were examined ultrastructurally in order to better define the fine structure of the causative organisms in parasitic conditions and to clarify the host- parasite relationships. Taking into account the few data in the literature regarding the same disorders in immunocompetent subjects, no striking differences in the morphology of the infectious agents or in the types of parasitism were found. Nevertheless, isolated herpesvirus and papillomavirus virions were found outside the infected cells, and this observation, if confirmed in a larger series of cases, could suggest a persistent infectivity of the lesions in immunocompromised patients. Moreover, electron microscopy proved to be useful for diagnostic purposes; in one case of disseminated cutaneous mycobacteriosis, repeated cultures failed to grow the organism.
AB - Tissue samples from 19 HIV-seropositive immunocompromised patients suffering from oral hairy leukoplakia, chronic vesicular or ulcerative herpes simplex, chronic nonmetameric herpes zoster, secondary syphilis, condylomata acuminata, molluscum contagiosum, or disseminated cutaneous mycobacteriosis were examined ultrastructurally in order to better define the fine structure of the causative organisms in parasitic conditions and to clarify the host- parasite relationships. Taking into account the few data in the literature regarding the same disorders in immunocompetent subjects, no striking differences in the morphology of the infectious agents or in the types of parasitism were found. Nevertheless, isolated herpesvirus and papillomavirus virions were found outside the infected cells, and this observation, if confirmed in a larger series of cases, could suggest a persistent infectivity of the lesions in immunocompromised patients. Moreover, electron microscopy proved to be useful for diagnostic purposes; in one case of disseminated cutaneous mycobacteriosis, repeated cultures failed to grow the organism.
KW - AIDS
KW - Chronic herpes simplex
KW - Chronic herpes zoster
KW - Condylomata acuminata
KW - Cutaneous mycobacteriosis
KW - Molluscum contagiosum
KW - Oral hairy leukoplakia
KW - Secondary syphilis
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UR - http://www.scopus.com/inward/citedby.url?scp=0027248110&partnerID=8YFLogxK
M3 - Article
VL - 15
SP - 320
EP - 325
JO - American Journal of Dermatopathology
JF - American Journal of Dermatopathology
SN - 0193-1091
IS - 4
ER -